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Disentanglement of Cape fur seals (Arctocephalus pusillus pusillus) with reversible medetomidine-midazolam-butorphanol

Anaesthesia in pinnipeds is considered a much higher risk than in most terrestrial mammals because of their frequent proximity to water and physiological and anatomical adaptations related to diving, which also influence their anaesthesia management. Anaesthetising and immobilising entangled seals d...

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Autores principales: Gardner, Brett R., Spolander, Brandon, Seakamela, S. Mduduzi, McCue, Steven A., Kotze, Pieter G.H., Musson, Maryke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182561/
https://www.ncbi.nlm.nih.gov/pubmed/34082540
http://dx.doi.org/10.4102/jsava.v92i0.2119
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author Gardner, Brett R.
Spolander, Brandon
Seakamela, S. Mduduzi
McCue, Steven A.
Kotze, Pieter G.H.
Musson, Maryke
author_facet Gardner, Brett R.
Spolander, Brandon
Seakamela, S. Mduduzi
McCue, Steven A.
Kotze, Pieter G.H.
Musson, Maryke
author_sort Gardner, Brett R.
collection PubMed
description Anaesthesia in pinnipeds is considered a much higher risk than in most terrestrial mammals because of their frequent proximity to water and physiological and anatomical adaptations related to diving, which also influence their anaesthesia management. Anaesthetising and immobilising entangled seals does not allow for selection of animals that are at a safe distance from the water’s edge. Medetomidine-midazolam-butorphanol (MMB) sedation was trialled on eight entangled Cape fur seals (CFS) (Arctocephalus pusillus pusillus) to determine if it was safe to use on animals that entered the water post-darting. The MMB was given at an estimated dose of 0.03 mg/kg, 0.2 mg/kg and 0.2 mg/kg, respectively, via remote darting. Sedation was reversed with intramuscular atipamezole (0.15 mg/kg) and naltrexone (0.4 mg/kg) to antagonise the effects of medetomidine and butorphanol, respectively. Moderate sedation was achieved in six animals. Six of the animals entered the water after being darted. There was a single mortality and a single animal that was too lightly sedated for capture. The preliminary results indicate that MMB produces suitable sedation for disentanglement of CFS. Additionally, MMB might be suitable for application to field-based biological research.
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spelling pubmed-81825612021-06-08 Disentanglement of Cape fur seals (Arctocephalus pusillus pusillus) with reversible medetomidine-midazolam-butorphanol Gardner, Brett R. Spolander, Brandon Seakamela, S. Mduduzi McCue, Steven A. Kotze, Pieter G.H. Musson, Maryke J S Afr Vet Assoc Original Research Anaesthesia in pinnipeds is considered a much higher risk than in most terrestrial mammals because of their frequent proximity to water and physiological and anatomical adaptations related to diving, which also influence their anaesthesia management. Anaesthetising and immobilising entangled seals does not allow for selection of animals that are at a safe distance from the water’s edge. Medetomidine-midazolam-butorphanol (MMB) sedation was trialled on eight entangled Cape fur seals (CFS) (Arctocephalus pusillus pusillus) to determine if it was safe to use on animals that entered the water post-darting. The MMB was given at an estimated dose of 0.03 mg/kg, 0.2 mg/kg and 0.2 mg/kg, respectively, via remote darting. Sedation was reversed with intramuscular atipamezole (0.15 mg/kg) and naltrexone (0.4 mg/kg) to antagonise the effects of medetomidine and butorphanol, respectively. Moderate sedation was achieved in six animals. Six of the animals entered the water after being darted. There was a single mortality and a single animal that was too lightly sedated for capture. The preliminary results indicate that MMB produces suitable sedation for disentanglement of CFS. Additionally, MMB might be suitable for application to field-based biological research. AOSIS 2021-05-21 /pmc/articles/PMC8182561/ /pubmed/34082540 http://dx.doi.org/10.4102/jsava.v92i0.2119 Text en © 2021. The Authors https://creativecommons.org/licenses/by/4.0/Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.
spellingShingle Original Research
Gardner, Brett R.
Spolander, Brandon
Seakamela, S. Mduduzi
McCue, Steven A.
Kotze, Pieter G.H.
Musson, Maryke
Disentanglement of Cape fur seals (Arctocephalus pusillus pusillus) with reversible medetomidine-midazolam-butorphanol
title Disentanglement of Cape fur seals (Arctocephalus pusillus pusillus) with reversible medetomidine-midazolam-butorphanol
title_full Disentanglement of Cape fur seals (Arctocephalus pusillus pusillus) with reversible medetomidine-midazolam-butorphanol
title_fullStr Disentanglement of Cape fur seals (Arctocephalus pusillus pusillus) with reversible medetomidine-midazolam-butorphanol
title_full_unstemmed Disentanglement of Cape fur seals (Arctocephalus pusillus pusillus) with reversible medetomidine-midazolam-butorphanol
title_short Disentanglement of Cape fur seals (Arctocephalus pusillus pusillus) with reversible medetomidine-midazolam-butorphanol
title_sort disentanglement of cape fur seals (arctocephalus pusillus pusillus) with reversible medetomidine-midazolam-butorphanol
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182561/
https://www.ncbi.nlm.nih.gov/pubmed/34082540
http://dx.doi.org/10.4102/jsava.v92i0.2119
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