NLRP3 ablation enhances tolerance in heat stroke pathology by inhibiting IL-1β-mediated neuroinflammation

BACKGROUND: Patients with prior illness are more vulnerable to heat stroke-induced injury, but the underlying mechanism is unknown. Recent studies suggested that NLRP3 inflammasome played an important role in the pathophysiology of heat stroke. METHODS: In this study, we used a classic animal heat s...

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Detalles Bibliográficos
Autores principales: Zhang, Zi-Teng, Gu, Xiao-Lei, Zhao, Xin, He, Xian, Shi, Hao-Wei, Zhang, Kun, Zhang, Yi-Ming, Su, Yi-Nan, Zhu, Jiang-Bo, Li, Zhi-Wei, Li, Guo-Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182902/
https://www.ncbi.nlm.nih.gov/pubmed/34092247
http://dx.doi.org/10.1186/s12974-021-02179-y

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