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Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway

BACKGROUND: Inflammatory osteolysis after total joint replacement (TJR) may cause implant failure, periprosthetic fractures, and be a severe threat to global public health. Our previous studies demonstrated that melatonin had a therapeutic effect on wear-particles induced osteolysis. Gut microbiota...

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Detalles Bibliográficos
Autores principales:	Wu, Yanglin, He, Fan, Zhang, Chenhui, Zhang, Qin, Su, Xinlin, Zhu, Xu, Liu, Ang, Shi, Weidong, Lin, Weifeng, Jin, Zhongqin, Yang, Huilin, Lin, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182936/ https://www.ncbi.nlm.nih.gov/pubmed/34092246 http://dx.doi.org/10.1186/s12951-021-00915-3

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