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NDRG1 regulates osteosarcoma cells via mediating the mitochondrial function and CSCs differentiation
BACKGROUND: Cancer stem cells (CSCs) are mainly contributed to malignancy metastatic potential and resistant therapy of osteosarcoma (OS). The mitochondria-related apoptosis was generally accepted as the target of tumor therapy. However, the effect of N-myc downstream-regulated gene 1 (NDRG1) on CSC...
Autores principales: | Zhao, Tong, Meng, Ying, Wang, Yongping, Wang, Wenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182938/ https://www.ncbi.nlm.nih.gov/pubmed/34099022 http://dx.doi.org/10.1186/s13018-021-02503-5 |
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