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Effects of RORγt overexpression on the murine central nervous system

OBJECTIVE: T helper 17 (Th17) cells are a subset of CD4(+) T cells that produce interleukin (IL)‐17A. Recent studies showed that an increase in circulating IL‐17A causes cognitive dysfunction, although it is unknown how increased systemic IL‐17A affects brain function. Using transgenic mice overexpr...

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Detalles Bibliográficos
Autores principales: Sasaki, Tetsuya, Nagata, Rei, Takahashi, Satoru, Takei, Yosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182958/
https://www.ncbi.nlm.nih.gov/pubmed/33547881
http://dx.doi.org/10.1002/npr2.12162