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Decreased nesting behavior, selective increases in locomotor activity in a novel environment, and paradoxically increased open arm exploration in Neurogranin knockout mice
AIMS: Neurogranin (NRGN) is a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. Recent studies suggest that NRGN is involved in neuropsychiatric disorders, including schizophrenia, ADHD, and Alzheimer's disease. Previous behavioral studies of Nrgn knockout (...
Autores principales: | Nakajima, Ryuichi, Hattori, Satoko, Funasaka, Teppei, Huang, Freesia L., Miyakawa, Tsuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182962/ https://www.ncbi.nlm.nih.gov/pubmed/33270377 http://dx.doi.org/10.1002/npr2.12150 |
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