SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator

SARS coronavirus-2 (SARS-CoV-2) is causing a global pandemic with large variation in COVID-19 disease spectrum. SARS-CoV-2 infection requires host receptor ACE2 on lung epithelium, but epithelial underpinnings of variation are largely unknown. We capitalized on comprehensive organoid assays to repor...

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Detalles Bibliográficos
Autores principales: Hysenaj, Lisiena, Little, Samantha, Kulhanek, Kayla, Gbenedio, Oghenekevwe M., Rodriguez, Lauren, Shen, Alan, Lone, Jean-Christophe, Lupin-Jimenez, Leonard C., Bonser, Luke R., Serwas, Nina K., Bahl, Kriti, Mick, Eran, Li, Jack Z., Ding, Vivianne W., Matsumoto, Shotaro, Maishan, Mazharul, Simoneau, Camille, Fragiadakis, Gabriela, Jablons, David M., Langelier, Charles R., Matthay, Michael, Ott, Melanie, Krummel, Matthew, Combes, Alexis J., Sil, Anita, Erle, David J., Kratz, Johannes R., Roose, Jeroen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183007/
https://www.ncbi.nlm.nih.gov/pubmed/34100012
http://dx.doi.org/10.1101/2021.06.01.446640

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