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Site-directed mutagenesis of the quorum-sensing transcriptional regulator SinR affects the biosynthesis of menaquinone in Bacillus subtilis

BACKGROUND: Menaquinone (MK-7) is a highly valuable vitamin K(2) produced by Bacillus subtilis. Common static metabolic engineering approaches for promoting the production of MK-7 have been studied previously. However, these approaches caused an accumulation of toxic substances and reduced product y...

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Detalles Bibliográficos
Autores principales:	Wu, Jing, Li, Wei, Zhao, Shi-guang, Qian, Sen-he, Wang, Zhou, Zhou, Meng-jie, Hu, Wen-song, Wang, Jian, Hu, Liu-xiu, Liu, Yan, Xue, Zheng-lian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183045/ https://www.ncbi.nlm.nih.gov/pubmed/34098969 http://dx.doi.org/10.1186/s12934-021-01603-5

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