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Glycosylation of β1 subunit plays a pivotal role in the toxin sensitivity and activation of BK channels

BACKGROUND: The accessory β1 subunits, regulating the pharmacological and biophysical properties of BK channels, always undergo post-translational modifications, especially glycosylation. To date, it remains elusive whether the glycosylation contributes to the regulation of BK channels by β1 subunit...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoli, Xiao, Qian, Zhu, Yudan, Qi, Hong, Qu, Dongxiao, Yao, Yu, Jia, Yuxiang, Guo, Jingkan, Cheng, Jiwei, Ji, Yonghua, Li, Guoyi, Tao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183112/
https://www.ncbi.nlm.nih.gov/pubmed/34149831
http://dx.doi.org/10.1590/1678-9199-JVATITD-2020-0182