Fructose Protects Against Acetaminophen‐Induced Hepatotoxicity Mainly by Activating the Carbohydrate‐Response Element‐Binding Protein α–Fibroblast Growth Factor 21 Axis in Mice

Acetaminophen (N‐acetyl‐para‐aminophenol [APAP]) overdose is the most common cause of drug‐induced liver injury in the Western world and has limited therapeutic options. As an important dietary component intake, fructose is mainly metabolized in liver, but its impact on APAP‐induced liver injury is...

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Detalles Bibliográficos
Autores principales: Zhang, Deqiang, Wang, Sujuan, Ospina, Erin, Shabandri, Omar, Lank, Daniel, Akakpo, Jephte Y., Zhao, Zifeng, Yang, Meichan, Wu, Jun, Jaeschke, Hartmut, Saha, Pradip, Tong, Xin, Yin, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183176/
https://www.ncbi.nlm.nih.gov/pubmed/34141985
http://dx.doi.org/10.1002/hep4.1683

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