Cargando…
Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer
A 67-year-old woman underwent a medical check-up by her general practitioner after complaining of atypical pain in the shoulder girdle. Due to the important inflammatory syndrome noticed on blood testing, a polymyalgia rheumatica was suspected and she was started on corticosteroid treatment with goo...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183193/ https://www.ncbi.nlm.nih.gov/pubmed/34088689 http://dx.doi.org/10.1136/bcr-2021-241938 |
_version_ | 1783704334134935552 |
---|---|
author | Dayer, Nicolas Fasquelle, François Salati, Emanuela Dietrich, Gilles |
author_facet | Dayer, Nicolas Fasquelle, François Salati, Emanuela Dietrich, Gilles |
author_sort | Dayer, Nicolas |
collection | PubMed |
description | A 67-year-old woman underwent a medical check-up by her general practitioner after complaining of atypical pain in the shoulder girdle. Due to the important inflammatory syndrome noticed on blood testing, a polymyalgia rheumatica was suspected and she was started on corticosteroid treatment with good clinical response, but no impact on inflammation. She underwent extensive imaging with a thoraco-abdominal CT scanner that demonstrated a pancreatic mass, then later a PET-CT showed 3 different hyperactive lesions. Biopsies then revealed simultaneous diffuse large B-cell lymphoma (DLBCL), colorectal adenocarcinoma and pancreatic neuroendocrine tumour. She benefited from low rectal endoscopic excision of the colorectal tumour, R-CHOP chemotherapy for DLBCL and laparoscopic left pancreatectomy. Successful treatment required a good multidisciplinary collaboration between the different specialists. The patient made a good recovery and achieved complete remission at 1 year. This an unusual presentation of multiple primary malignancies. |
format | Online Article Text |
id | pubmed-8183193 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-81831932021-07-01 Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer Dayer, Nicolas Fasquelle, François Salati, Emanuela Dietrich, Gilles BMJ Case Rep Case Report A 67-year-old woman underwent a medical check-up by her general practitioner after complaining of atypical pain in the shoulder girdle. Due to the important inflammatory syndrome noticed on blood testing, a polymyalgia rheumatica was suspected and she was started on corticosteroid treatment with good clinical response, but no impact on inflammation. She underwent extensive imaging with a thoraco-abdominal CT scanner that demonstrated a pancreatic mass, then later a PET-CT showed 3 different hyperactive lesions. Biopsies then revealed simultaneous diffuse large B-cell lymphoma (DLBCL), colorectal adenocarcinoma and pancreatic neuroendocrine tumour. She benefited from low rectal endoscopic excision of the colorectal tumour, R-CHOP chemotherapy for DLBCL and laparoscopic left pancreatectomy. Successful treatment required a good multidisciplinary collaboration between the different specialists. The patient made a good recovery and achieved complete remission at 1 year. This an unusual presentation of multiple primary malignancies. BMJ Publishing Group 2021-06-04 /pmc/articles/PMC8183193/ /pubmed/34088689 http://dx.doi.org/10.1136/bcr-2021-241938 Text en © BMJ Publishing Group Limited 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Case Report Dayer, Nicolas Fasquelle, François Salati, Emanuela Dietrich, Gilles Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer |
title | Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer |
title_full | Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer |
title_fullStr | Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer |
title_full_unstemmed | Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer |
title_short | Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer |
title_sort | multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183193/ https://www.ncbi.nlm.nih.gov/pubmed/34088689 http://dx.doi.org/10.1136/bcr-2021-241938 |
work_keys_str_mv | AT dayernicolas multipleprimarymalignanciessynchronouslymphomapancreaticneuroendocrinetumourandcolorectalcancer AT fasquellefrancois multipleprimarymalignanciessynchronouslymphomapancreaticneuroendocrinetumourandcolorectalcancer AT salatiemanuela multipleprimarymalignanciessynchronouslymphomapancreaticneuroendocrinetumourandcolorectalcancer AT dietrichgilles multipleprimarymalignanciessynchronouslymphomapancreaticneuroendocrinetumourandcolorectalcancer |