Cargando…

Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer

A 67-year-old woman underwent a medical check-up by her general practitioner after complaining of atypical pain in the shoulder girdle. Due to the important inflammatory syndrome noticed on blood testing, a polymyalgia rheumatica was suspected and she was started on corticosteroid treatment with goo...

Descripción completa

Detalles Bibliográficos
Autores principales: Dayer, Nicolas, Fasquelle, François, Salati, Emanuela, Dietrich, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183193/
https://www.ncbi.nlm.nih.gov/pubmed/34088689
http://dx.doi.org/10.1136/bcr-2021-241938
_version_ 1783704334134935552
author Dayer, Nicolas
Fasquelle, François
Salati, Emanuela
Dietrich, Gilles
author_facet Dayer, Nicolas
Fasquelle, François
Salati, Emanuela
Dietrich, Gilles
author_sort Dayer, Nicolas
collection PubMed
description A 67-year-old woman underwent a medical check-up by her general practitioner after complaining of atypical pain in the shoulder girdle. Due to the important inflammatory syndrome noticed on blood testing, a polymyalgia rheumatica was suspected and she was started on corticosteroid treatment with good clinical response, but no impact on inflammation. She underwent extensive imaging with a thoraco-abdominal CT scanner that demonstrated a pancreatic mass, then later a PET-CT showed 3 different hyperactive lesions. Biopsies then revealed simultaneous diffuse large B-cell lymphoma (DLBCL), colorectal adenocarcinoma and pancreatic neuroendocrine tumour. She benefited from low rectal endoscopic excision of the colorectal tumour, R-CHOP chemotherapy for DLBCL and laparoscopic left pancreatectomy. Successful treatment required a good multidisciplinary collaboration between the different specialists. The patient made a good recovery and achieved complete remission at 1 year. This an unusual presentation of multiple primary malignancies.
format Online
Article
Text
id pubmed-8183193
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-81831932021-07-01 Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer Dayer, Nicolas Fasquelle, François Salati, Emanuela Dietrich, Gilles BMJ Case Rep Case Report A 67-year-old woman underwent a medical check-up by her general practitioner after complaining of atypical pain in the shoulder girdle. Due to the important inflammatory syndrome noticed on blood testing, a polymyalgia rheumatica was suspected and she was started on corticosteroid treatment with good clinical response, but no impact on inflammation. She underwent extensive imaging with a thoraco-abdominal CT scanner that demonstrated a pancreatic mass, then later a PET-CT showed 3 different hyperactive lesions. Biopsies then revealed simultaneous diffuse large B-cell lymphoma (DLBCL), colorectal adenocarcinoma and pancreatic neuroendocrine tumour. She benefited from low rectal endoscopic excision of the colorectal tumour, R-CHOP chemotherapy for DLBCL and laparoscopic left pancreatectomy. Successful treatment required a good multidisciplinary collaboration between the different specialists. The patient made a good recovery and achieved complete remission at 1 year. This an unusual presentation of multiple primary malignancies. BMJ Publishing Group 2021-06-04 /pmc/articles/PMC8183193/ /pubmed/34088689 http://dx.doi.org/10.1136/bcr-2021-241938 Text en © BMJ Publishing Group Limited 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Case Report
Dayer, Nicolas
Fasquelle, François
Salati, Emanuela
Dietrich, Gilles
Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer
title Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer
title_full Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer
title_fullStr Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer
title_full_unstemmed Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer
title_short Multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer
title_sort multiple primary malignancies: synchronous lymphoma, pancreatic neuroendocrine tumour and colorectal cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183193/
https://www.ncbi.nlm.nih.gov/pubmed/34088689
http://dx.doi.org/10.1136/bcr-2021-241938
work_keys_str_mv AT dayernicolas multipleprimarymalignanciessynchronouslymphomapancreaticneuroendocrinetumourandcolorectalcancer
AT fasquellefrancois multipleprimarymalignanciessynchronouslymphomapancreaticneuroendocrinetumourandcolorectalcancer
AT salatiemanuela multipleprimarymalignanciessynchronouslymphomapancreaticneuroendocrinetumourandcolorectalcancer
AT dietrichgilles multipleprimarymalignanciessynchronouslymphomapancreaticneuroendocrinetumourandcolorectalcancer