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Type 17 immunity promotes the exhaustion of CD8(+) T cells in cancer

BACKGROUND: Multiple types of immune cells producing IL-17 are found in the tumor microenvironment. However, their roles in tumor progression and exhaustion of CD8(+) tumor-infiltrating lymphocytes (TILs) remain unclear. METHODS: To determine the role of type 17 immunity in tumor, we investigated th...

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Detalles Bibliográficos
Autores principales: Kim, Byung-Seok, Kuen, Da-Sol, Koh, Choong-Hyun, Kim, Hyung-Don, Chang, Seon Hee, Kim, Sehui, Jeon, Yoon Kyung, Park, Young-Jun, Choi, Garam, Kim, Jiyeon, Kang, Keon Wook, Kim, Hye Young, Kang, Suk-Jo, Hwang, Shin, Shin, Eui-Cheol, Kang, Chang-Yuil, Dong, Chen, Chung, Yeonseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183213/
https://www.ncbi.nlm.nih.gov/pubmed/34083422
http://dx.doi.org/10.1136/jitc-2021-002603