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Design, synthesis and immunological evaluation of self-assembled antigenic peptides from dual-antigen targets: a broad-spectrum candidate for an effective antibreast cancer therapy
BACKGROUND: Considering the narrow immune response spectrum of a single epitope, and the nanoparticles (NPs) as a novel adjuvant can achieve efficient delivery of antigenic peptides safely, a nano-system (denoted as DSPE-PEG-Man@EM-NPs) based on cathepsin B-responsive antigenic peptides was designed...
Autores principales: | Shi, Wei, Qiu, Qianqian, Feng, Ziying, Tong, Zhenzhen, Guo, Weiwei, Zou, Feng, Yue, Na, Huang, Wenlong, Qian, Hai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183215/ https://www.ncbi.nlm.nih.gov/pubmed/34083420 http://dx.doi.org/10.1136/jitc-2021-002523 |
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