A rare neurendocrine tumor of the lung: sclerosing paraganglioma. A neoplasm that is difficult to diagnose and a source of dangerous pitfalls. A case report and literature review

An endobronchial obstructing neoformation was found in a 58-year-old man. The histology and immunohistochemical profile oriented the authors towards a diagnosis of paraganglioma, sclerosing variant. This very difficult diagnosis, especially in a pulmonary localization, may lead to erroneous conclusi...

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Autores principales: Africa, Giovanni, Plutino, Francesca M., Filotico, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore srl 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183351/
https://www.ncbi.nlm.nih.gov/pubmed/33393521
http://dx.doi.org/10.32074/1591-951X-23-19
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author Africa, Giovanni
Plutino, Francesca M.
Filotico, Marcello
author_facet Africa, Giovanni
Plutino, Francesca M.
Filotico, Marcello
author_sort Africa, Giovanni
collection PubMed
description An endobronchial obstructing neoformation was found in a 58-year-old man. The histology and immunohistochemical profile oriented the authors towards a diagnosis of paraganglioma, sclerosing variant. This very difficult diagnosis, especially in a pulmonary localization, may lead to erroneous conclusions both in terms of histogenetic interpretation and that of its biological behavior. The pulmonary localization of the paraganglioma is very rare and even more rare the sclerosing variant, recently reported. Differential diagnosis and literature are discussed.
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spelling pubmed-81833512021-07-08 A rare neurendocrine tumor of the lung: sclerosing paraganglioma. A neoplasm that is difficult to diagnose and a source of dangerous pitfalls. A case report and literature review Africa, Giovanni Plutino, Francesca M. Filotico, Marcello Pathologica Original Article An endobronchial obstructing neoformation was found in a 58-year-old man. The histology and immunohistochemical profile oriented the authors towards a diagnosis of paraganglioma, sclerosing variant. This very difficult diagnosis, especially in a pulmonary localization, may lead to erroneous conclusions both in terms of histogenetic interpretation and that of its biological behavior. The pulmonary localization of the paraganglioma is very rare and even more rare the sclerosing variant, recently reported. Differential diagnosis and literature are discussed. Pacini Editore srl 2020-12-01 /pmc/articles/PMC8183351/ /pubmed/33393521 http://dx.doi.org/10.32074/1591-951X-23-19 Text en © 2020 Copyright by Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access journal distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license: the work can be used by mentioning the author and the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en
spellingShingle Original Article
Africa, Giovanni
Plutino, Francesca M.
Filotico, Marcello
A rare neurendocrine tumor of the lung: sclerosing paraganglioma. A neoplasm that is difficult to diagnose and a source of dangerous pitfalls. A case report and literature review
title A rare neurendocrine tumor of the lung: sclerosing paraganglioma. A neoplasm that is difficult to diagnose and a source of dangerous pitfalls. A case report and literature review
title_full A rare neurendocrine tumor of the lung: sclerosing paraganglioma. A neoplasm that is difficult to diagnose and a source of dangerous pitfalls. A case report and literature review
title_fullStr A rare neurendocrine tumor of the lung: sclerosing paraganglioma. A neoplasm that is difficult to diagnose and a source of dangerous pitfalls. A case report and literature review
title_full_unstemmed A rare neurendocrine tumor of the lung: sclerosing paraganglioma. A neoplasm that is difficult to diagnose and a source of dangerous pitfalls. A case report and literature review
title_short A rare neurendocrine tumor of the lung: sclerosing paraganglioma. A neoplasm that is difficult to diagnose and a source of dangerous pitfalls. A case report and literature review
title_sort rare neurendocrine tumor of the lung: sclerosing paraganglioma. a neoplasm that is difficult to diagnose and a source of dangerous pitfalls. a case report and literature review
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183351/
https://www.ncbi.nlm.nih.gov/pubmed/33393521
http://dx.doi.org/10.32074/1591-951X-23-19
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