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CMTM6-Deficient Monocytes in ANCA-Associated Vasculitis Fail to Present the Immune Checkpoint PD-L1

OBJECTIVES: ANCA-associated vasculitides (AAV) affect small- and medium-sized blood vessels. In active disease, vessel wall infiltrates are mainly composed of monocytes and macrophages. Immune checkpoint molecules are crucial for the maintenance of self-tolerance and the prevention of autoimmune dis...

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Detalles Bibliográficos
Autores principales:	Zeisbrich, Markus, Chevalier, Nina, Sehnert, Bettina, Rizzi, Marta, Venhoff, Nils, Thiel, Jens, Voll, Reinhard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183471/ https://www.ncbi.nlm.nih.gov/pubmed/34108971 http://dx.doi.org/10.3389/fimmu.2021.673912

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