Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells

The vast majority (>90%) of glioblastoma (GBM) patients belong to the isocitrate dehydrogenase 1 wild type (IDH1(WT)) group which exhibits a poor prognosis with a median survival of less than 15 months. This study demonstrated numerous immunosuppressive genes as well as β-catenin gene, pivotal fo...

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Detalles Bibliográficos
Autores principales: Fan, Dandan, Yue, Qi, Chen, Jian, Wang, Cong, Yu, Ruilin, Jin, Ziyi, Yin, Shujie, Wang, Qinyue, Chen, Luo, Liao, Xueling, Peng, Chengyuan, Zhang, Jianpin, Cao, Zhonglian, Mao, Ying, Huang, Ruimin, Chen, Liang, Li, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183516/
https://www.ncbi.nlm.nih.gov/pubmed/34123575
http://dx.doi.org/10.1080/2162402X.2021.1932061

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