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Low-dose HDACi potentiates anti-tumor activity of macrophages in immunotherapy

The success of checkpoint immunotherapy has created optimism that cancer may be curable. However, not all patients respond, resistance is common and many patients relapse owing to immune escape. We demonstrate that HDAC inhibition not only decreases the trafficking of myeloid-derived suppressor cell...

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Detalles Bibliográficos
Autores principales: Li, Xiaolei, Dai, Hanren, Wang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183541/
https://www.ncbi.nlm.nih.gov/pubmed/34123577
http://dx.doi.org/10.1080/2162402X.2021.1935668