S-ketamine in patient-controlled analgesia reduces opioid consumption in a dose-dependent manner after major lumbar fusion surgery: A randomized, double-blind, placebo-controlled clinical trial

BACKGROUND: Spinal fusion surgery causes severe pain. Strong opioids, commonly used as postoperative analgesics, may have unwanted side effects. S-ketamine may be an effective analgesic adjuvant in opioid patient-controlled analgesia (PCA). However, the optimal adjunct S-ketamine dose to reduce post...

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Detalles Bibliográficos
Autores principales: Brinck, Elina C. V., Virtanen, Taru, Mäkelä, Sanna, Soini, Venla, Hynninen, Ville-Veikko, Mulo, Jukka, Savolainen, Urmas, Rantakokko, Juho, Maisniemi, Kreu, Liukas, Antti, Olkkola, Klaus T., Kontinen, Vesa, Tarkkila, Pekka, Peltoniemi, Marko, Saari, Teijo I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8183989/
https://www.ncbi.nlm.nih.gov/pubmed/34097713
http://dx.doi.org/10.1371/journal.pone.0252626

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