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Yeast Fin1-PP1 dephosphorylates an Ipl1 substrate, Ndc80, to remove Bub1-Bub3 checkpoint proteins from the kinetochore during anaphase

The spindle assembly checkpoint (SAC) prevents anaphase onset in response to chromosome attachment defects, and SAC silencing is essential for anaphase onset. Following anaphase onset, activated Cdc14 phosphatase dephosphorylates the substrates of cyclin-dependent kinase to facilitate anaphase progr...

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Detalles Bibliográficos
Autores principales: Bokros, Michael, Sherwin, Delaney, Kabbaj, Marie-Helene, Wang, Yanchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184001/
https://www.ncbi.nlm.nih.gov/pubmed/34033659
http://dx.doi.org/10.1371/journal.pgen.1009592