Cargando…

Yeast Fin1-PP1 dephosphorylates an Ipl1 substrate, Ndc80, to remove Bub1-Bub3 checkpoint proteins from the kinetochore during anaphase

The spindle assembly checkpoint (SAC) prevents anaphase onset in response to chromosome attachment defects, and SAC silencing is essential for anaphase onset. Following anaphase onset, activated Cdc14 phosphatase dephosphorylates the substrates of cyclin-dependent kinase to facilitate anaphase progr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bokros, Michael, Sherwin, Delaney, Kabbaj, Marie-Helene, Wang, Yanchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184001/ https://www.ncbi.nlm.nih.gov/pubmed/34033659 http://dx.doi.org/10.1371/journal.pgen.1009592

Ejemplares similares

Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans
por: Kim, Taekyung, et al.
Publicado: (2015)

Correction: Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans
por: Kim, Taekyung, et al.
Publicado: (2016)

Checkpoint Proteins Bub1 and Bub3 Delay Anaphase Onset in Response to Low Tension Independent of Microtubule-Kinetochore Detachment
por: Proudfoot, Kathleen G., et al.
Publicado: (2019)

BUB-1 makes kinetochores MAD
por: Short, Ben
Publicado: (2014)

Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint
por: Zhang, Gang, et al.
Publicado: (2015)

The Human Homologue of Bub3 Is Required for Kinetochore Localization of Bub1 and a Mad3/Bub1-related Protein Kinase
por: Taylor, Stephen S., et al.
Publicado: (1998)

BubR1 recruitment to the kinetochore via Bub1 enhances spindle assembly checkpoint signaling
por: Banerjee, Anand, et al.
Publicado: (2022)

The phosphorylation of a kinetochore protein Dam1 by Aurora B/Ipl1 kinase promotes chromosome bipolar attachment in yeast
por: Jin, Fengzhi, et al.
Publicado: (2017)

The Crystal Structure of the N-Terminal Region of BUB1 Provides Insight into the Mechanism of BUB1 Recruitment to Kinetochores
por: Bolanos-Garcia, Victor M., et al.
Publicado: (2009)

Expression and prognosis analyses of BUB1, BUB1B and BUB3 in human sarcoma
por: Long, Zeling, et al.
Publicado: (2021)

Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1
por: Fischer, Elyse S, et al.
Publicado: (2021)

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
por: Ditchfield, Claire, et al.
Publicado: (2003)

Bub1 targeting to centromeres is sufficient for Sgo1 recruitment in the absence of kinetochores
por: Williams, Samantha J., et al.
Publicado: (2016)

Bub1 regulates chromosome segregation in a kinetochore-independent manner
por: Klebig, Christiane, et al.
Publicado: (2009)

BUB-1 promotes amphitelic chromosome biorientation via multiple activities at the kinetochore
por: Edwards, Frances, et al.
Publicado: (2018)

Spindle Checkpoint Protein Bub1 Is Required for Kinetochore Localization of Mad1, Mad2, Bub3, and Cenp-E, Independently of Its Kinase Activity
por: Sharp-Baker, Hilary, et al.
Publicado: (2001)

Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint
por: London, Nitobe, et al.
Publicado: (2014)

BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis
por: Singh, Priyanka, et al.
Publicado: (2021)

The Ndc80 complex targets Bod1 to human mitotic kinetochores
por: Schleicher, Katharina, et al.
Publicado: (2017)

Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit
por: Huang, Haomin, et al.
Publicado: (2008)

Kinetochore-bound Mps1 regulates kinetochore–microtubule attachments via Ndc80 phosphorylation
por: Sarangapani, Krishna K., et al.
Publicado: (2021)

A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint
por: Overlack, Katharina, et al.
Publicado: (2015)

Stable kinetochore‐microtubule attachment requires loop‐dependent Ndc80‐Ndc80 binding
por: Polley, Soumitra, et al.
Publicado: (2023)

Segregating Bub1's mitotic functions
por: Short, Ben
Publicado: (2012)

BUB1-bling over with Possibilities
por: Barcellos-Hoff, Mary Helen
Publicado: (2015)

BubR1 and brain aging
por: Hussaini, Syed Mohammed Qasim, et al.
Publicado: (2017)

Bub1 kinase in the regulation of mitosis
por: Kim, Taekyung, et al.
Publicado: (2021)

Arrayed BUB recruitment modules in the kinetochore scaffold KNL1 promote accurate chromosome segregation
por: Vleugel, Mathijs, et al.
Publicado: (2013)

Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation
por: Asghar, Adeel, et al.
Publicado: (2015)

Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation
por: Zhang, Gang, et al.
Publicado: (2016)

Hec1/Ndc80 Tail Domain Function at the Kinetochore-Microtubule Interface
por: Wimbish, Robert T., et al.
Publicado: (2020)

Differential requirement for Bub1 and Bub3 in regulation of meiotic versus mitotic chromosome segregation
por: Cairo, Gisela, et al.
Publicado: (2020)

Structural analysis reveals features of the spindle checkpoint kinase Bub1–kinetochore subunit Knl1 interaction
por: Krenn, Veronica, et al.
Publicado: (2012)

Bub1 and Bub3 promote the conversion from monopolar to bipolar chromosome attachment independently of shugoshin
por: Windecker, Hanna, et al.
Publicado: (2009)

Defining the Molecular Basis of BubR1 Kinetochore Interactions and APC/C-CDC20 Inhibition
por: D'Arcy, Sheena, et al.
Publicado: (2010)

Ccp1-Ndc80 switch at the N terminus of CENP-T regulates kinetochore assembly
por: Dong, Qianhua, et al.
Publicado: (2021)

BubR1 checks in with CENP-E
por: LeBrasseur, Nicole
Publicado: (2003)

Bub1-Mediated Adaptation of the Spindle Checkpoint
por: Goto, Greicy H., et al.
Publicado: (2011)

BubR1 shows self-control
por: Short, Ben
Publicado: (2012)

BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1
por: Chen, Rey-Huei
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_gkt2imodpheq28l250h4trhgl4