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The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency
Human pluripotent stem cells (PSCs) express human endogenous retrovirus type-H (HERV-H), which exists as more than a thousand copies on the human genome and frequently produces chimeric transcripts as long-non-coding RNAs (lncRNAs) fused with downstream neighbor genes. Previous studies showed that H...
Autores principales: | Takahashi, Kazutoshi, Nakamura, Michiko, Okubo, Chikako, Kliesmete, Zane, Ohnuki, Mari, Narita, Megumi, Watanabe, Akira, Ueda, Mai, Takashima, Yasuhiro, Hellmann, Ines, Yamanaka, Shinya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184003/ https://www.ncbi.nlm.nih.gov/pubmed/34033652 http://dx.doi.org/10.1371/journal.pgen.1009587 |
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