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The Exon Junction Complex and intron removal prevent re-splicing of mRNA

Accurate splice site selection is critical for fruitful gene expression. Recently, the mammalian EJC was shown to repress competing, cryptic, splice sites (SS). However, the evolutionary generality of this remains unclear. Here, we demonstrate the Drosophila EJC suppresses hundreds of functional cry...

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Detalles Bibliográficos
Autores principales: Joseph, Brian, Lai, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184009/
https://www.ncbi.nlm.nih.gov/pubmed/34033644
http://dx.doi.org/10.1371/journal.pgen.1009563

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