Voltage-clamp fluorometry analysis of structural rearrangements of ATP-gated channel P2X2 upon hyperpolarization

Gating of the ATP-activated channel P2X2 has been shown to be dependent not only on [ATP] but also on membrane voltage, despite the absence of a canonical voltage-sensor domain. We aimed to investigate the structural rearrangements of rat P2X2 during ATP- and voltage-dependent gating, using a voltag...

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Detalles Bibliográficos
Autores principales: Andriani, Rizki Tsari, Kubo, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184218/
https://www.ncbi.nlm.nih.gov/pubmed/34009126
http://dx.doi.org/10.7554/eLife.65822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184218/
https://www.ncbi.nlm.nih.gov/pubmed/34009126
http://dx.doi.org/10.7554/eLife.65822

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