Multi-Organ Transcriptome Dynamics in a Mouse Model of Cecal Ligation and Puncture-Induced Polymicrobial Sepsis

PURPOSE: During sepsis, an excessive inflammatory immune reaction contributes to multi-organ dysfunction syndrome (MODS), a critical condition associated with high morbidity and mortality; however, the molecular mechanisms driving MODS remain elusive. METHODS: We used RNA sequencing to characterize...

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Detalles Bibliográficos
Autores principales: Rumienczyk, Izabela, Kulecka, Maria, Ostrowski, Jerzy, Mar, Daniel, Bomsztyk, Karol, Standage, Stephen W, Mikula, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184233/
https://www.ncbi.nlm.nih.gov/pubmed/34113146
http://dx.doi.org/10.2147/JIR.S307305

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