IgA Vasculitis in a Lung Cancer Patient During Chemoradiotherapy

A 72-year-old man with locally advanced lung squamous cell carcinoma experienced red purpura on the lower legs and hematuria when the disease progressed during definitive chemoradiotherapy. He had renal dysfunction and proteinuria. Biopsy specimens of the skin lesion and kidney revealed immunoglobul...

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Autores principales: Taoka, Masataka, Ochi, Nobuaki, Mimura, Ayaka, Ichiyama, Naruhiko, Nagasaki, Yasunari, Nakagawa, Nozomu, Nakanishi, Hidekazu, Yamane, Hiromichi, Oshiro, Yoshiyuki, Monobe, Yasumasa, Takigawa, Nagio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184282/
https://www.ncbi.nlm.nih.gov/pubmed/34113114
http://dx.doi.org/10.2147/TCRM.S308771
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author Taoka, Masataka
Ochi, Nobuaki
Mimura, Ayaka
Ichiyama, Naruhiko
Nagasaki, Yasunari
Nakagawa, Nozomu
Nakanishi, Hidekazu
Yamane, Hiromichi
Oshiro, Yoshiyuki
Monobe, Yasumasa
Takigawa, Nagio
author_facet Taoka, Masataka
Ochi, Nobuaki
Mimura, Ayaka
Ichiyama, Naruhiko
Nagasaki, Yasunari
Nakagawa, Nozomu
Nakanishi, Hidekazu
Yamane, Hiromichi
Oshiro, Yoshiyuki
Monobe, Yasumasa
Takigawa, Nagio
author_sort Taoka, Masataka
collection PubMed
description A 72-year-old man with locally advanced lung squamous cell carcinoma experienced red purpura on the lower legs and hematuria when the disease progressed during definitive chemoradiotherapy. He had renal dysfunction and proteinuria. Biopsy specimens of the skin lesion and kidney revealed immunoglobulin A vasculitis. Potential causes such as paraneoplastic syndrome and cancer treatment have been proposed. The administration of steroids rapidly improved the symptoms. The presentation of immunoglobulin A vasculitis is accompanied by malignancies. Clinicians should keep this syndrome in mind, even during curative-intent treatment.
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spelling pubmed-81842822021-06-09 IgA Vasculitis in a Lung Cancer Patient During Chemoradiotherapy Taoka, Masataka Ochi, Nobuaki Mimura, Ayaka Ichiyama, Naruhiko Nagasaki, Yasunari Nakagawa, Nozomu Nakanishi, Hidekazu Yamane, Hiromichi Oshiro, Yoshiyuki Monobe, Yasumasa Takigawa, Nagio Ther Clin Risk Manag Case Report A 72-year-old man with locally advanced lung squamous cell carcinoma experienced red purpura on the lower legs and hematuria when the disease progressed during definitive chemoradiotherapy. He had renal dysfunction and proteinuria. Biopsy specimens of the skin lesion and kidney revealed immunoglobulin A vasculitis. Potential causes such as paraneoplastic syndrome and cancer treatment have been proposed. The administration of steroids rapidly improved the symptoms. The presentation of immunoglobulin A vasculitis is accompanied by malignancies. Clinicians should keep this syndrome in mind, even during curative-intent treatment. Dove 2021-06-03 /pmc/articles/PMC8184282/ /pubmed/34113114 http://dx.doi.org/10.2147/TCRM.S308771 Text en © 2021 Taoka et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Taoka, Masataka
Ochi, Nobuaki
Mimura, Ayaka
Ichiyama, Naruhiko
Nagasaki, Yasunari
Nakagawa, Nozomu
Nakanishi, Hidekazu
Yamane, Hiromichi
Oshiro, Yoshiyuki
Monobe, Yasumasa
Takigawa, Nagio
IgA Vasculitis in a Lung Cancer Patient During Chemoradiotherapy
title IgA Vasculitis in a Lung Cancer Patient During Chemoradiotherapy
title_full IgA Vasculitis in a Lung Cancer Patient During Chemoradiotherapy
title_fullStr IgA Vasculitis in a Lung Cancer Patient During Chemoradiotherapy
title_full_unstemmed IgA Vasculitis in a Lung Cancer Patient During Chemoradiotherapy
title_short IgA Vasculitis in a Lung Cancer Patient During Chemoradiotherapy
title_sort iga vasculitis in a lung cancer patient during chemoradiotherapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184282/
https://www.ncbi.nlm.nih.gov/pubmed/34113114
http://dx.doi.org/10.2147/TCRM.S308771
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