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Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis

Spermatocytic seminoma is a relatively rare testicular tumor and is characterized by a good prognosis. The discovery of a sarcomatous contingent modifies the prognosis of the indolent neoplasm. Only 20 cases being reported in English literature. We present the case of a 66-year-old man with a two-ye...

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Autores principales: Chennoufi, Mehdi, Boukhannous, Ibrahim, Mokhtari, Mohamed, El Moudane, Anouar, Barki, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184520/
https://www.ncbi.nlm.nih.gov/pubmed/34141586
http://dx.doi.org/10.1016/j.eucr.2021.101732
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author Chennoufi, Mehdi
Boukhannous, Ibrahim
Mokhtari, Mohamed
El Moudane, Anouar
Barki, Ali
author_facet Chennoufi, Mehdi
Boukhannous, Ibrahim
Mokhtari, Mohamed
El Moudane, Anouar
Barki, Ali
author_sort Chennoufi, Mehdi
collection PubMed
description Spermatocytic seminoma is a relatively rare testicular tumor and is characterized by a good prognosis. The discovery of a sarcomatous contingent modifies the prognosis of the indolent neoplasm. Only 20 cases being reported in English literature. We present the case of a 66-year-old man with a two-year history of left-sided scrotal pain and swelling. Tumor markers were normal. Ultrasound demonstrated a very large solid-cystic testicular mass. Orchidectomy was performed. Further imaging investigations revealed lung, vertebra, and retroperitoneal lymph node metastases. Histological examination and immunohistochemistry of the orchidectomy specimen concluded on spermatocytic seminoma associated with undifferentiated sarcoma component.
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spelling pubmed-81845202021-06-16 Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis Chennoufi, Mehdi Boukhannous, Ibrahim Mokhtari, Mohamed El Moudane, Anouar Barki, Ali Urol Case Rep Oncology Spermatocytic seminoma is a relatively rare testicular tumor and is characterized by a good prognosis. The discovery of a sarcomatous contingent modifies the prognosis of the indolent neoplasm. Only 20 cases being reported in English literature. We present the case of a 66-year-old man with a two-year history of left-sided scrotal pain and swelling. Tumor markers were normal. Ultrasound demonstrated a very large solid-cystic testicular mass. Orchidectomy was performed. Further imaging investigations revealed lung, vertebra, and retroperitoneal lymph node metastases. Histological examination and immunohistochemistry of the orchidectomy specimen concluded on spermatocytic seminoma associated with undifferentiated sarcoma component. Elsevier 2021-05-28 /pmc/articles/PMC8184520/ /pubmed/34141586 http://dx.doi.org/10.1016/j.eucr.2021.101732 Text en © 2021 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Chennoufi, Mehdi
Boukhannous, Ibrahim
Mokhtari, Mohamed
El Moudane, Anouar
Barki, Ali
Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis
title Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis
title_full Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis
title_fullStr Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis
title_full_unstemmed Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis
title_short Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis
title_sort spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: a review and case report analysis
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184520/
https://www.ncbi.nlm.nih.gov/pubmed/34141586
http://dx.doi.org/10.1016/j.eucr.2021.101732
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