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Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis
Spermatocytic seminoma is a relatively rare testicular tumor and is characterized by a good prognosis. The discovery of a sarcomatous contingent modifies the prognosis of the indolent neoplasm. Only 20 cases being reported in English literature. We present the case of a 66-year-old man with a two-ye...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184520/ https://www.ncbi.nlm.nih.gov/pubmed/34141586 http://dx.doi.org/10.1016/j.eucr.2021.101732 |
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author | Chennoufi, Mehdi Boukhannous, Ibrahim Mokhtari, Mohamed El Moudane, Anouar Barki, Ali |
author_facet | Chennoufi, Mehdi Boukhannous, Ibrahim Mokhtari, Mohamed El Moudane, Anouar Barki, Ali |
author_sort | Chennoufi, Mehdi |
collection | PubMed |
description | Spermatocytic seminoma is a relatively rare testicular tumor and is characterized by a good prognosis. The discovery of a sarcomatous contingent modifies the prognosis of the indolent neoplasm. Only 20 cases being reported in English literature. We present the case of a 66-year-old man with a two-year history of left-sided scrotal pain and swelling. Tumor markers were normal. Ultrasound demonstrated a very large solid-cystic testicular mass. Orchidectomy was performed. Further imaging investigations revealed lung, vertebra, and retroperitoneal lymph node metastases. Histological examination and immunohistochemistry of the orchidectomy specimen concluded on spermatocytic seminoma associated with undifferentiated sarcoma component. |
format | Online Article Text |
id | pubmed-8184520 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-81845202021-06-16 Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis Chennoufi, Mehdi Boukhannous, Ibrahim Mokhtari, Mohamed El Moudane, Anouar Barki, Ali Urol Case Rep Oncology Spermatocytic seminoma is a relatively rare testicular tumor and is characterized by a good prognosis. The discovery of a sarcomatous contingent modifies the prognosis of the indolent neoplasm. Only 20 cases being reported in English literature. We present the case of a 66-year-old man with a two-year history of left-sided scrotal pain and swelling. Tumor markers were normal. Ultrasound demonstrated a very large solid-cystic testicular mass. Orchidectomy was performed. Further imaging investigations revealed lung, vertebra, and retroperitoneal lymph node metastases. Histological examination and immunohistochemistry of the orchidectomy specimen concluded on spermatocytic seminoma associated with undifferentiated sarcoma component. Elsevier 2021-05-28 /pmc/articles/PMC8184520/ /pubmed/34141586 http://dx.doi.org/10.1016/j.eucr.2021.101732 Text en © 2021 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Oncology Chennoufi, Mehdi Boukhannous, Ibrahim Mokhtari, Mohamed El Moudane, Anouar Barki, Ali Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis |
title | Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis |
title_full | Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis |
title_fullStr | Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis |
title_full_unstemmed | Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis |
title_short | Spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: A review and case report analysis |
title_sort | spermatocytic seminoma of testis associated with undifferentiated sarcoma revealed in metastatic disease: a review and case report analysis |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184520/ https://www.ncbi.nlm.nih.gov/pubmed/34141586 http://dx.doi.org/10.1016/j.eucr.2021.101732 |
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