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Population pharmacokinetic modelling to quantify the magnitude of drug-drug interactions between amlodipine and antiretroviral drugs

PURPOSE: Drug-drug interactions (DDIs) with antiretroviral drugs (ARVs) represent an important issue in elderly people living with HIV (PLWH). Amlodipine is a commonly prescribed antihypertensive drug metabolized by CYP3A4, thus predisposed to a risk of DDIs. Guidance on the management of DDIs is mo...

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Detalles Bibliográficos
Autores principales:	Courlet, Perrine, Guidi, Monia, Alves Saldanha, Susana, Cavassini, Matthias, Stoeckle, Marcel, Buclin, Thierry, Marzolini, Catia, Decosterd, Laurent A., Csajka, Chantal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Pharmacokinetics and Disposition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184532/ https://www.ncbi.nlm.nih.gov/pubmed/33452585 http://dx.doi.org/10.1007/s00228-020-03060-2

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