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A country-specific FRAX model for Botswana

INTRODUCTION: Hip fracture rates in Botswana were used to create a FRAX® model for fracture risk assessment. OBJECTIVE: This paper describes the development and characteristics of a country-specific FRAX model for Botswana. METHODS: Age-specific and sex-specific incidence of hip fracture and nationa...

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Detalles Bibliográficos
Autores principales: Kebaetse, M., Nkhwa, S., Mogodi, M., Masunge, J., Gureja, Y. P., Ramabu, M., Mmopelwa, T., Sharif, I., Orford, A., Harvey, N. C., McCloskey, E. V., Cauley, J. A., Kanis, J. A., Johansson, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184541/
https://www.ncbi.nlm.nih.gov/pubmed/34100118
http://dx.doi.org/10.1007/s11657-021-00965-y
Descripción
Sumario:INTRODUCTION: Hip fracture rates in Botswana were used to create a FRAX® model for fracture risk assessment. OBJECTIVE: This paper describes the development and characteristics of a country-specific FRAX model for Botswana. METHODS: Age-specific and sex-specific incidence of hip fracture and national mortality rates was incorporated into a FRAX model for Botswana. Ten-year fracture probabilities were compared with those from African countries having a FRAX model and African Americans from the USA. RESULTS: The probabilities of hip fracture and major osteoporotic fracture were low compared with those from South Africa (Black and Coloured) and US Blacks. Probabilities were marginally higher than for Tunisia. CONCLUSION: The creation of a FRAX model is expected to help guide decisions about the prevention and treatment of fragility fractures in Botswana.