A country-specific FRAX model for Botswana

INTRODUCTION: Hip fracture rates in Botswana were used to create a FRAX® model for fracture risk assessment. OBJECTIVE: This paper describes the development and characteristics of a country-specific FRAX model for Botswana. METHODS: Age-specific and sex-specific incidence of hip fracture and nationa...

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Autores principales: Kebaetse, M., Nkhwa, S., Mogodi, M., Masunge, J., Gureja, Y. P., Ramabu, M., Mmopelwa, T., Sharif, I., Orford, A., Harvey, N. C., McCloskey, E. V., Cauley, J. A., Kanis, J. A., Johansson, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184541/
https://www.ncbi.nlm.nih.gov/pubmed/34100118
http://dx.doi.org/10.1007/s11657-021-00965-y
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author Kebaetse, M.
Nkhwa, S.
Mogodi, M.
Masunge, J.
Gureja, Y. P.
Ramabu, M.
Mmopelwa, T.
Sharif, I.
Orford, A.
Harvey, N. C.
McCloskey, E. V.
Cauley, J. A.
Kanis, J. A.
Johansson, H.
author_facet Kebaetse, M.
Nkhwa, S.
Mogodi, M.
Masunge, J.
Gureja, Y. P.
Ramabu, M.
Mmopelwa, T.
Sharif, I.
Orford, A.
Harvey, N. C.
McCloskey, E. V.
Cauley, J. A.
Kanis, J. A.
Johansson, H.
author_sort Kebaetse, M.
collection PubMed
description INTRODUCTION: Hip fracture rates in Botswana were used to create a FRAX® model for fracture risk assessment. OBJECTIVE: This paper describes the development and characteristics of a country-specific FRAX model for Botswana. METHODS: Age-specific and sex-specific incidence of hip fracture and national mortality rates was incorporated into a FRAX model for Botswana. Ten-year fracture probabilities were compared with those from African countries having a FRAX model and African Americans from the USA. RESULTS: The probabilities of hip fracture and major osteoporotic fracture were low compared with those from South Africa (Black and Coloured) and US Blacks. Probabilities were marginally higher than for Tunisia. CONCLUSION: The creation of a FRAX model is expected to help guide decisions about the prevention and treatment of fragility fractures in Botswana.
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spelling pubmed-81845412021-06-25 A country-specific FRAX model for Botswana Kebaetse, M. Nkhwa, S. Mogodi, M. Masunge, J. Gureja, Y. P. Ramabu, M. Mmopelwa, T. Sharif, I. Orford, A. Harvey, N. C. McCloskey, E. V. Cauley, J. A. Kanis, J. A. Johansson, H. Arch Osteoporos Original Article INTRODUCTION: Hip fracture rates in Botswana were used to create a FRAX® model for fracture risk assessment. OBJECTIVE: This paper describes the development and characteristics of a country-specific FRAX model for Botswana. METHODS: Age-specific and sex-specific incidence of hip fracture and national mortality rates was incorporated into a FRAX model for Botswana. Ten-year fracture probabilities were compared with those from African countries having a FRAX model and African Americans from the USA. RESULTS: The probabilities of hip fracture and major osteoporotic fracture were low compared with those from South Africa (Black and Coloured) and US Blacks. Probabilities were marginally higher than for Tunisia. CONCLUSION: The creation of a FRAX model is expected to help guide decisions about the prevention and treatment of fragility fractures in Botswana. Springer London 2021-06-07 2021 /pmc/articles/PMC8184541/ /pubmed/34100118 http://dx.doi.org/10.1007/s11657-021-00965-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Kebaetse, M.
Nkhwa, S.
Mogodi, M.
Masunge, J.
Gureja, Y. P.
Ramabu, M.
Mmopelwa, T.
Sharif, I.
Orford, A.
Harvey, N. C.
McCloskey, E. V.
Cauley, J. A.
Kanis, J. A.
Johansson, H.
A country-specific FRAX model for Botswana
title A country-specific FRAX model for Botswana
title_full A country-specific FRAX model for Botswana
title_fullStr A country-specific FRAX model for Botswana
title_full_unstemmed A country-specific FRAX model for Botswana
title_short A country-specific FRAX model for Botswana
title_sort country-specific frax model for botswana
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184541/
https://www.ncbi.nlm.nih.gov/pubmed/34100118
http://dx.doi.org/10.1007/s11657-021-00965-y
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