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Evolutionary Conservation of Structural and Functional Coupling between the BRM AT-Hook and Bromodomain

The BAF chromatin remodeling complex is critical for genome regulation. The central ATPase of BAF is either BRM or BRG1, both of which contain a C-terminal bromodomain, known to associate with acetylated lysines. We have recently demonstrated that in addition to acetyl-lysine binding, the BRG1/BRM b...

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Detalles Bibliográficos
Autores principales: Lupo, Brianna E., Chu, Peirou, Harms, Michael J., Morrison, Emma A., Musselman, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184587/
https://www.ncbi.nlm.nih.gov/pubmed/33539881
http://dx.doi.org/10.1016/j.jmb.2021.166845