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HIF‐1α is necessary for activation and tumour‐promotion effect of cancer‐associated fibroblasts in lung cancer

Cancer‐associated fibroblasts (CAFs) activation is crucial for the establishment of a tumour promoting microenvironment, but our understanding of CAFs activation is still limited. In this study, we found that hypoxia‐inducible factor‐1α (HIF‐1α) was highly expressed in CAFs of human lung cancer tiss...

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Detalles Bibliográficos
Autores principales: Zhang, Yana, Bian, Yangyang, Wang, Yuan, Wang, Yuanyuan, Duan, Xixi, Han, Yuning, Zhang, Lijing, Wang, Fei, Gu, Zhuoyu, Qin, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184678/
https://www.ncbi.nlm.nih.gov/pubmed/33943003
http://dx.doi.org/10.1111/jcmm.16556