Cargando…
Sulfasalazine, a potent suppressor of gastric cancer proliferation and metastasis by inhibition of xCT: Conventional drug in new use
The aim of this study was to explore the role of sulfasalazine on proliferation and metastasis in gastric cancer by inhibition of xCT. The relationships between clinical characteristics and xCT expression were analysed. An immunohistochemical staining assay and Western blot were performed among gast...
Autores principales: | Zhuang, Jinfu, Liu, Xing, Yang, Yuanfeng, Zhang, Yiyi, Guan, Guoxian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184680/ https://www.ncbi.nlm.nih.gov/pubmed/33988296 http://dx.doi.org/10.1111/jcmm.16548 |
Ejemplares similares
-
Sulfasalazine Sensitizes Polyhematoporphyrin-Mediated Photodynamic Therapy in Cholangiocarcinoma by Targeting xCT
por: Zheng, Yan-Wen, et al.
Publicado: (2021) -
High expression of CD44v9 and xCT in chemoresistant hepatocellular carcinoma: Potential targets by sulfasalazine
por: Wada, Fumitaka, et al.
Publicado: (2018) -
xCT inhibitor sulfasalazine depletes paclitaxel-resistant tumor cells through ferroptosis in uterine serous carcinoma
por: Sugiyama, Akiko, et al.
Publicado: (2020) -
Sulfasalazine could modulate the CD44v9‐xCT system and enhance cisplatin‐induced cytotoxic effects in metastatic bladder cancer
por: Ogihara, Koichiro, et al.
Publicado: (2019) -
Participation of xCT in melanoma cell proliferation in vitro and tumorigenesis in vivo
por: Shin, Seung-Shick, et al.
Publicado: (2018)