Cargando…
NRP1 and MMP9 are dual targets of RNA‐binding protein QKI5 to alter VEGF‐R/ NRP1 signalling in trophoblasts in preeclampsia
Preeclampsia (PE) is characterized by placental ischemia and hypoxia, resulting in abnormal casting of the uterine spiral artery, which is mainly caused by insufficient trophoblastic cell infiltration. A reduction in levels of growth factor‐based signalling via Neuropilin‐1 (NRP1) has been shown to...
Autores principales: | Yang, Xingyu, Chen, Dan, He, Biwei, Cheng, Weiwei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184681/ https://www.ncbi.nlm.nih.gov/pubmed/33942999 http://dx.doi.org/10.1111/jcmm.16580 |
Ejemplares similares
-
VEGF(189) binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain
por: Tillo, Miguel, et al.
Publicado: (2015) -
Expression of NRP-1 and NRP-2 in Endometrial Cancer
por: Oplawski, Marcin, et al.
Publicado: (2019) -
Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis
por: Fantin, Alessandro, et al.
Publicado: (2014) -
VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation
por: Herzog, Birger, et al.
Publicado: (2011) -
Segregation Analysis of Rare NRP1 and NRP2 Variants in Families with Lymphedema
por: Michelini, Sandro, et al.
Publicado: (2020)