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Pharmacokinetics and pharmacodynamics of ampreloxetine, a novel, selective norepinephrine reuptake inhibitor, in symptomatic neurogenic orthostatic hypotension

PURPOSE: Ampreloxetine is a novel, selective, long-acting norepinephrine reuptake (NET) inhibitor being investigated as a once-daily oral treatment for symptomatic neurogenic orthostatic hypotension (nOH) in patients with autonomic synucleinopathies. The purpose of this study was to characterize the...

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Detalles Bibliográficos
Autores principales: Lo, Arthur, Norcliffe-Kaufmann, Lucy, Vickery, Ross, Bourdet, David, Kanodia, Jitendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184714/
https://www.ncbi.nlm.nih.gov/pubmed/33782836
http://dx.doi.org/10.1007/s10286-021-00800-x