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Diurnal preference and depressive symptomatology: a meta-analysis
Eveningness, a preference for later sleep and rise times, has been associated with a number of negative outcomes in terms of both physical and mental health. A large body of evidence links eveningness to Major Depressive Disorder (MDD). However, to date, evidence quantifying this association is limi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184740/ https://www.ncbi.nlm.nih.gov/pubmed/34099766 http://dx.doi.org/10.1038/s41598-021-91205-3 |
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author | Norbury, Ray |
author_facet | Norbury, Ray |
author_sort | Norbury, Ray |
collection | PubMed |
description | Eveningness, a preference for later sleep and rise times, has been associated with a number of negative outcomes in terms of both physical and mental health. A large body of evidence links eveningness to Major Depressive Disorder (MDD). However, to date, evidence quantifying this association is limited. The current meta-analysis included 43 effect sizes from a total 27,996 participants. Using a random-effects model it was demonstrated that eveningness is associated with a small effect size (Fisher’s Z = − 2.4, 95% CI [− 0.27. − 0.21], p < 0.001). Substantial heterogeneity between studies was observed, with meta-regression analyses demonstrating a significant effect of mean age on the association between diurnal preference and depression. There was also evidence of potential publication bias as assessed by visual inspection of funnel plots and Egger’s test. The association between diurnal preference and depression is small in magnitude and heterogenous. A better understanding of the mechanistic underpinnings linking diurnal preference to depression and suitably powered prospective studies that allow causal inference are required. |
format | Online Article Text |
id | pubmed-8184740 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-81847402021-06-08 Diurnal preference and depressive symptomatology: a meta-analysis Norbury, Ray Sci Rep Article Eveningness, a preference for later sleep and rise times, has been associated with a number of negative outcomes in terms of both physical and mental health. A large body of evidence links eveningness to Major Depressive Disorder (MDD). However, to date, evidence quantifying this association is limited. The current meta-analysis included 43 effect sizes from a total 27,996 participants. Using a random-effects model it was demonstrated that eveningness is associated with a small effect size (Fisher’s Z = − 2.4, 95% CI [− 0.27. − 0.21], p < 0.001). Substantial heterogeneity between studies was observed, with meta-regression analyses demonstrating a significant effect of mean age on the association between diurnal preference and depression. There was also evidence of potential publication bias as assessed by visual inspection of funnel plots and Egger’s test. The association between diurnal preference and depression is small in magnitude and heterogenous. A better understanding of the mechanistic underpinnings linking diurnal preference to depression and suitably powered prospective studies that allow causal inference are required. Nature Publishing Group UK 2021-06-07 /pmc/articles/PMC8184740/ /pubmed/34099766 http://dx.doi.org/10.1038/s41598-021-91205-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Norbury, Ray Diurnal preference and depressive symptomatology: a meta-analysis |
title | Diurnal preference and depressive symptomatology: a meta-analysis |
title_full | Diurnal preference and depressive symptomatology: a meta-analysis |
title_fullStr | Diurnal preference and depressive symptomatology: a meta-analysis |
title_full_unstemmed | Diurnal preference and depressive symptomatology: a meta-analysis |
title_short | Diurnal preference and depressive symptomatology: a meta-analysis |
title_sort | diurnal preference and depressive symptomatology: a meta-analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184740/ https://www.ncbi.nlm.nih.gov/pubmed/34099766 http://dx.doi.org/10.1038/s41598-021-91205-3 |
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