Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission

In the absence of a prophylactic vaccine, the use of antiretroviral therapy (ART) as pre-exposure prophylaxis (PrEP) to prevent HIV acquisition by uninfected individuals is a promising approach to slowing the epidemic, but its efficacy is hampered by incomplete patient adherence and ART-resistant va...

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Detalles Bibliográficos
Autores principales: Chang, Xiao L., Webb, Gabriela M., Wu, Helen L., Greene, Justin M., Abdulhaqq, Shaheed, Bateman, Katherine B., Reed, Jason S., Pessoa, Cleiton, Weber, Whitney C., Maier, Nicholas, Chew, Glen M., Gilbride, Roxanne M., Gao, Lina, Agnor, Rebecca, Giobbi, Travis, Torgerson, Jeffrey, Siess, Don, Burnett, Nicole, Fischer, Miranda, Shiel, Oriene, Moats, Cassandra, Patterson, Bruce, Dhody, Kush, Kelly, Scott, Pourhassan, Nader, Magnani, Diogo M., Smedley, Jeremy, Bimber, Benjamin N., Haigwood, Nancy L., Hansen, Scott G., Brown, Timothy R., Ndhlovu, Lishomwa C., Sacha, Jonah B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184841/
https://www.ncbi.nlm.nih.gov/pubmed/34099693
http://dx.doi.org/10.1038/s41467-021-23697-6

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