Cargando…

Ibrutinib does not prevent kidney fibrosis following acute and chronic injury

Recent studies suggested that ibrutinib, a Bruton tyrosine kinase (BTK) inhibitor, developed for the treatment of chronic lymphocytic leukemia, may prevent NLRP3 inflammasome activation in macrophages, IL-1β secretion and subsequent development of inflammation and organ fibrosis. The role of NLRP3 h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Belliere, Julie, Casemayou, Audrey, Colliou, Eloïse, El Hachem, Hélène, Kounde, Clément, Piedrafita, Alexis, Feuillet, Guylène, Schanstra, Joost P., Faguer, Stanislas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184891/ https://www.ncbi.nlm.nih.gov/pubmed/34099830 http://dx.doi.org/10.1038/s41598-021-91491-x

Ejemplares similares

Avacopan as First-Line Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Steroid-Sparing Option
por: Gabilan, Charlotte, et al.
Publicado: (2022)

A single dose of estrogen during hemorrhagic shock protects against Kidney Injury whereas estrogen restoration in ovariectomized mice is ineffective
por: Buléon, Marie, et al.
Publicado: (2020)

Kidney Involvement in Patients With Chronic Myelomonocytic Leukemia or BCR-ABL–Negative Myeloproliferative Neoplasms
por: Belliere, Julie, et al.
Publicado: (2020)

Are serum C3 levels or kidney C3 deposits useful markers for predicting outcomes in patients with ANCA-associated vasculitis?
por: Cassard, Alexis, et al.
Publicado: (2023)

The tryptophan pathway and nicotinamide supplementation in ischaemic acute kidney injury
por: Piedrafita, Alexis, et al.
Publicado: (2021)

Hnf-1β Transcription Factor Is an Early Hif-1α-Independent Marker of Epithelial Hypoxia and Controls Renal Repair
por: Faguer, Stanislas, et al.
Publicado: (2013)

A universal predictive and mechanistic urinary peptide signature in acute kidney injury
por: Piedrafita, Alexis, et al.
Publicado: (2022)

Heparin-free regional anticoagulation of haemodialysis filters with calcium-free dialysate: is citrate mandatory?
por: Medrano, Chloé, et al.
Publicado: (2021)

IL6-R blocking with tocilizumab in critically ill patients with hemophagocytic syndrome
por: Dufranc, Etienne, et al.
Publicado: (2020)

Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells
por: Maggiorani, Damien, et al.
Publicado: (2015)

Acute interstitial nephritis related to immune checkpoint inhibitors
por: Belliere, Julie, et al.
Publicado: (2016)

Spectrum of Kidney Disorders Associated with T-Cell Immunoclones
por: Piedrafita, Alexis, et al.
Publicado: (2022)

UMOD genetic variations and myeloma cast nephropathy
por: Belliere, Julie, et al.
Publicado: (2019)

Leucine-Rich Alpha-2 Glycoprotein 1 Accumulates in Complicated Atherosclerosis and Promotes Calcification
por: Grzesiak, Lucile, et al.
Publicado: (2023)

Publisher Correction to: A universal predictive and mechanistic urinary peptide signature in acute kidney injury
por: Piedrafita, Alexis, et al.
Publicado: (2022)

Systems biology combining human- and animal-data miRNA and mRNA data identifies new targets in ureteropelvic junction obstruction
por: Papadopoulos, Theofilos, et al.
Publicado: (2017)

Apelin affects the mouse aging urinary peptidome with minimal effects on kidney
por: Vinel, Claire, et al.
Publicado: (2019)

Predictive Factors for Humoral Response After 2-dose SARS-CoV-2 Vaccine in Solid Organ Transplant Patients
por: Marion, Olivier, et al.
Publicado: (2021)

Role of C5 inhibition in Idiopathic Inflammatory Myopathies and Scleroderma Renal Crisis–Induced Thrombotic Microangiopathies
por: Gouin, Anna, et al.
Publicado: (2021)

Controlling Ibrutinib’s Conformations about Its Heterobiaryl Axis to Increase BTK Selectivity
por: Toenjes, Sean T., et al.
Publicado: (2023)

Connectivity mapping of glomerular proteins identifies dimethylaminoparthenolide as a new inhibitor of diabetic kidney disease
por: Klein, Julie, et al.
Publicado: (2020)

Outcomes of Older Patients (≥60 years) with New-Onset Idiopathic Nephrotic Syndrome Receiving Immunosuppressive Regimen: A Multicentre Study of 116 Patients
por: Colliou, Eloïse, et al.
Publicado: (2019)

Unmasking Silent Endothelial Activation in the Cardiovascular System Using Molecular Magnetic Resonance Imaging
por: Belliere, Julie, et al.
Publicado: (2015)

Developing a kidney and urinary pathway knowledge base
por: Jupp, Simon, et al.
Publicado: (2011)

Mutations in the RARE and MARE regulatory sequences of HNF1β are not a frequent cause of kidney/urinary tract malformation
por: Faguer, Stanislas, et al.
Publicado: (2009)

Short- and long-term renal outcomes following severe rhabdomyolysis: a French multicenter retrospective study of 387 patients
por: Candela, Nelly, et al.
Publicado: (2020)

Complement C5 inhibition reverses bleomycin-induced thrombotic microangiopathy
por: Salhi, Sofiane, et al.
Publicado: (2020)

Urinary Peptides as Potential Non-Invasive Biomarkers for Lupus Nephritis: Results of the Peptidu-LUP Study
por: Tailliar, Maxence, et al.
Publicado: (2021)

Ibrutinib-induced cardiomyopathy
por: Kyi, Htay Htay, et al.
Publicado: (2019)

Extrahepatic metabolism of ibrutinib
por: Rood, Johannes J. M., et al.
Publicado: (2020)

‘Prevention is better than cure’: warning for comedications in patients receiving immune checkpoint inhibitors to avoid acute kidney injury
por: Belliere, Julie, et al.
Publicado: (2022)

Anti-SARS-CoV-2 spike protein and neutralizing antibodies at 1 and 3 months after three doses of SARS-CoV-2 vaccine in a large cohort of solid organ transplant patients
por: Kamar, Nassim, et al.
Publicado: (2022)

Does Ibrutinib impact outcomes of viral infection by SARS-CoV-2 in mantle cell lymphoma patients?
por: Alsuliman, Tamim, et al.
Publicado: (2021)

Ibrutinib: Rebound effect in the form of respiratory deterioration following the discontinuation of ibrutinib: case report
Publicado: (2021)

A High-Throughput Clinical Laboratory Methodology for the Therapeutic Monitoring of Ibrutinib and Dihydrodiol Ibrutinib
por: Karvaly, Gellért Balázs, et al.
Publicado: (2022)

Collagen-Derived Peptides in CKD: A Link to Fibrosis
por: Mavrogeorgis, Emmanouil, et al.
Publicado: (2021)

Ibrutinib for B cell malignancies
por: Novero, Aileen, et al.
Publicado: (2014)

Ibrutinib-Induced Skin Rash
por: Kirar, Sudhir, et al.
Publicado: (2021)

Ibrutinib: Pneumonitis: case report
Publicado: (2021)

Arrhythmia Patterns in Patients on Ibrutinib
por: Fazal, Muhammad, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_18omcl1d5f0dpahgdugu88hqd5