Cargando…

PIWIL2 interacting with IKK to regulate autophagy and apoptosis in esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) is one of the most common malignancies and cause of death from cancer in China. Previous studies showed that autophagy and apoptosis inhibition are critical for the survival of ESCC cells. However, the underlying mechanisms remain to be clarified. Recently,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Xu, Huang, Lian, Lu, Yilu, Jiang, Wenhao, Song, Yue, Qiu, Bojun, Tao, Dachang, Liu, Yunqiang, Ma, Yongxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184941/ https://www.ncbi.nlm.nih.gov/pubmed/33469229 http://dx.doi.org/10.1038/s41418-020-00725-4

Ejemplares similares

Piwil2 Suppresses P53 by Inducing Phosphorylation of Signal Transducer and Activator of Transcription 3 in Tumor Cells
por: Lu, Yilu, et al.
Publicado: (2012)

Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK
por: Lu, Yilu, et al.
Publicado: (2017)

PIWIL2 suppresses Siah2-mediated degradation of HDAC3 and facilitates CK2α-mediated HDAC3 phosphorylation
por: Zhang, Yingying, et al.
Publicado: (2018)

PIWIL1 suppresses circadian rhythms through GSK3β‐induced phosphorylation and degradation of CLOCK and BMAL1 in cancer cells
por: Tan, Hao, et al.
Publicado: (2019)

PIWIL2 induces c-Myc expression by interacting with NME2 and regulates c-Myc-mediated tumor cell proliferation
por: Yao, Youlin, et al.
Publicado: (2014)

PIWIL1 destabilizes microtubule by suppressing phosphorylation at Ser16 and RLIM-mediated degradation of stathmin1
por: Li, Chao, et al.
Publicado: (2015)

RAE1 promotes BMAL1 shuttling and regulates degradation and activity of CLOCK: BMAL1 heterodimer
por: Zheng, Xulei, et al.
Publicado: (2019)

Co-expression of Piwil2/Piwil4 in nucleus indicates poor prognosis of hepatocellular carcinoma
por: Zeng, Guangping, et al.
Publicado: (2016)

HILI Inhibits TGF-β Signaling by Interacting with Hsp90 and Promoting TβR Degradation
por: Zhang, Kun, et al.
Publicado: (2012)

Decreased expression levels of PIWIL1, PIWIL2, and PIWIL4 are associated with worse survival in renal cell carcinoma patients
por: Iliev, Robert, et al.
Publicado: (2016)

HILI destabilizes microtubules by suppressing phosphorylation and Gigaxonin-mediated degradation of TBCB
por: Tan, Hao, et al.
Publicado: (2017)

The Clinical Significance of PIWIL3 and PIWIL4 Expression in Pancreatic Cancer
por: Li, Weiyao, et al.
Publicado: (2020)

The Prognosis Value of PIWIL1 and PIWIL2 Expression in Pancreatic Cancer
por: Li, Weiyao, et al.
Publicado: (2019)

The clinical significances of the abnormal expressions of Piwil1 and Piwil2 in colonic adenoma and adenocarcinoma
por: Wang, Hai-Ling, et al.
Publicado: (2015)

Epigenetic modifications promote the expression of the orphan nuclear receptor NR0B1 in human lung adenocarcinoma cells
por: Lu, Yongjie, et al.
Publicado: (2016)

Molecular cloning and expression analysis of a zebrafish novel zinc finger protein gene rnf141
por: Deng, Wenqian, et al.
Publicado: (2009)

Targeted disruption of the mouse testis-enriched gene Znf230 does not affect spermatogenesis or fertility
por: Liu, Yunqiang, et al.
Publicado: (2014)

Expression and Regulation of PIWIL-Proteins and PIWI-Interacting RNAs in Rheumatoid Arthritis
por: Pleštilová, Lenka, et al.
Publicado: (2016)

Dysfunction of apoptosis and autophagy correlates with local recurrence in esophageal squamous cell carcinoma after definitive chemoradiation
por: Qiu, Hu, et al.
Publicado: (2021)

PIWIL2 Regulates the Proliferation, Apoptosis and Colony Formation of Colorectal Cancer Cell Line
por: Kishani Farahani, Roya, et al.
Publicado: (2023)

Selective degradation of IKKα by autophagy is essential for arsenite-induced cancer cell apoptosis
por: Tan, Qixing, et al.
Publicado: (2020)

Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling
por: Feng, Y, et al.
Publicado: (2014)

MiR-126 promotes esophageal squamous cell carcinoma via inhibition of apoptosis and autophagy
por: Li, Mingli, et al.
Publicado: (2020)

Clinicopathologic Implications of PIWIL2 Expression in Colorectal Cancer
por: Oh, Sun-Ju, et al.
Publicado: (2012)

PIWIL1 governs the crosstalk of cancer cell metabolism and immunosuppressive microenvironment in hepatocellular carcinoma
por: Wang, Ning, et al.
Publicado: (2021)

Znf45l affects primitive hematopoiesis by regulating transforming growth factor-β signaling
por: Chen, Huijuan, et al.
Publicado: (2014)

Demethylation of CpG islands in the 5' upstream regions mediates the expression of the human testis-specific gene MAGEB16 and its mouse homolog Mageb16
por: Liu, Yunqiang, et al.
Publicado: (2014)

Survival and prognostic factors of patients with esophageal fistula in advanced esophageal squamous cell carcinoma
por: Guan, Xin, et al.
Publicado: (2020)

Novel function of PIWIL1 in neuronal polarization and migration via regulation of microtubule-associated proteins
por: Zhao, Ping-ping, et al.
Publicado: (2015)

PIWIL3 Forms a Complex with TDRKH in Mammalian Oocytes
por: Tan, Minjie, et al.
Publicado: (2020)

Inhibiting autophagy enhances sulforaphane-induced apoptosis via targeting NRF2 in esophageal squamous cell carcinoma
por: Lu, Zhaoming, et al.
Publicado: (2021)

Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells
por: Wang, Yan-Yang, et al.
Publicado: (2015)

Dichloroacetate induces protective autophagy in esophageal squamous carcinoma cells
por: Jia, Hong-Yu, et al.
Publicado: (2017)

Biomarkers of apoptosis and survival in esophageal squamous cell carcinoma
por: Takikita, Mikiko, et al.
Publicado: (2009)

Erratum to: Novel function of PIWIL1 in neuronal polarization and migration via regulation of microtubule-associated proteins
por: Zhao, Ping-ping, et al.
Publicado: (2016)

Exosomes derived from Piwil2-induced cancer stem cells transform fibroblasts into cancer-associated fibroblasts
por: Zhang, Dan, et al.
Publicado: (2020)

Exosomes derived from Piwil2-induced cancer stem cells transform fibroblasts into cancer-associated fibroblasts
por: Zhang, Dan, et al.
Publicado: (2022)

Identification of Piwil2-Like (PL2L) Proteins that Promote Tumorigenesis
por: Ye, Yin, et al.
Publicado: (2010)

Expression Status of PIWIL1 as a Prognostic Marker of Colorectal Cancer
por: Sun, Rui, et al.
Publicado: (2017)

Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression
por: Huang, Haidong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_n956rdrsagorgs8ka7sse49k7g