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Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells

Disruption of lymphatic lipid transport is linked to obesity and type 2 diabetes (T2D), but regulation of lymphatic vessel function and its link to disease remain unclear. Here we show that intestinal lymphatic endothelial cells (LECs) have an increasing CD36 expression from lymphatic capillaries (l...

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Detalles Bibliográficos
Autores principales: Cifarelli, Vincenza, Appak-Baskoy, Sila, Peche, Vivek S., Kluzak, Andrew, Shew, Trevor, Narendran, Ramkumar, Pietka, Kathryn M., Cella, Marina, Walls, Curtis W., Czepielewski, Rafael, Ivanov, Stoyan, Randolph, Gwendalyn J., Augustin, Hellmut G., Abumrad, Nada A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184948/
https://www.ncbi.nlm.nih.gov/pubmed/34099721
http://dx.doi.org/10.1038/s41467-021-23808-3