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Assessment of protein–protein interfaces in cryo-EM derived assemblies

Structures of macromolecular assemblies derived from cryo-EM maps often contain errors that become more abundant with decreasing resolution. Despite efforts in the cryo-EM community to develop metrics for map and atomistic model validation, thus far, no specific scoring metrics have been applied sys...

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Detalles Bibliográficos
Autores principales: Malhotra, Sony, Joseph, Agnel Praveen, Thiyagalingam, Jeyan, Topf, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184972/
https://www.ncbi.nlm.nih.gov/pubmed/34099703
http://dx.doi.org/10.1038/s41467-021-23692-x