A multicentre validation study of the diagnostic value of plasma neurofilament light

Increased cerebrospinal fluid neurofilament light (NfL) is a recognized biomarker for neurodegeneration that can also be assessed in blood. Here, we investigate plasma NfL as a marker of neurodegeneration in 13 neurodegenerative disorders, Down syndrome, depression and cognitively unimpaired control...

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Autores principales: Ashton, Nicholas J., Janelidze, Shorena, Al Khleifat, Ahmad, Leuzy, Antoine, van der Ende, Emma L., Karikari, Thomas K., Benedet, Andrea L., Pascoal, Tharick A., Lleó, Alberto, Parnetti, Lucilla, Galimberti, Daniela, Bonanni, Laura, Pilotto, Andrea, Padovani, Alessandro, Lycke, Jan, Novakova, Lenka, Axelsson, Markus, Velayudhan, Latha, Rabinovici, Gil D., Miller, Bruce, Pariante, Carmine, Nikkheslat, Naghmeh, Resnick, Susan M., Thambisetty, Madhav, Schöll, Michael, Fernández-Eulate, Gorka, Gil-Bea, Francisco J., López de Munain, Adolfo, Al-Chalabi, Ammar, Rosa-Neto, Pedro, Strydom, Andre, Svenningsson, Per, Stomrud, Erik, Santillo, Alexander, Aarsland, Dag, van Swieten, John C., Palmqvist, Sebastian, Zetterberg, Henrik, Blennow, Kaj, Hye, Abdul, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185001/
https://www.ncbi.nlm.nih.gov/pubmed/34099648
http://dx.doi.org/10.1038/s41467-021-23620-z

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