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Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer
Despite advances in the development of highly effective androgen receptor (AR)-directed therapies for the treatment of men with advanced prostate cancer, acquired resistance to such therapies frequently ensues. A significant subset of patients with resistant disease develop AR-negative tumors that l...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185096/ https://www.ncbi.nlm.nih.gov/pubmed/34099734 http://dx.doi.org/10.1038/s41467-021-23780-y |