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Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer
Despite advances in the development of highly effective androgen receptor (AR)-directed therapies for the treatment of men with advanced prostate cancer, acquired resistance to such therapies frequently ensues. A significant subset of patients with resistant disease develop AR-negative tumors that l...
Autores principales: | Brady, Nicholas J., Bagadion, Alyssa M., Singh, Richa, Conteduca, Vincenza, Van Emmenis, Lucie, Arceci, Elisa, Pakula, Hubert, Carelli, Ryan, Khani, Francesca, Bakht, Martin, Sigouros, Michael, Bareja, Rohan, Sboner, Andrea, Elemento, Olivier, Tagawa, Scott, Nanus, David M., Loda, Massimo, Beltran, Himisha, Robinson, Brian, Rickman, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185096/ https://www.ncbi.nlm.nih.gov/pubmed/34099734 http://dx.doi.org/10.1038/s41467-021-23780-y |
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