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Rhodobacter azotoformans LPS (RAP99-LPS) Is a TLR4 Agonist That Inhibits Lung Metastasis and Enhances TLR3-Mediated Chemokine Expression
The lipopolysaccharides (LPSs) of Rhodobacter are reported to be TLR4 antagonists. Accordingly, the extract of Rhodobacter azotoformans (RAP99) is used as a health supplement for humans and animals in Japan to regulate immune responses in vivo. We previously analyzed the LPS structure of RAP99 (RAP9...
Autores principales: | Murakami, Kaoru, Kamimura, Daisuke, Hasebe, Rie, Uchida, Mona, Abe, Nobuya, Yamamoto, Reiji, Jiang, Jing-Jing, Hidaka, Yasuhiro, Nakanishi, Yuko, Fujita, Shuzo, Toda, Yuki, Toda, Nobuhiro, Tanaka, Hiroki, Akira, Shizuo, Tanaka, Yuki, Murakami, Masaaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185171/ https://www.ncbi.nlm.nih.gov/pubmed/34113349 http://dx.doi.org/10.3389/fimmu.2021.675909 |
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