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D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling
BACKGROUND: Emphysematous COPD is characterized by aberrant alveolar repair. Macrophage migration inhibitory factor (MIF) contributes to alveolar repair, but for its structural and functional homolog D-dopachrome tautomerase (DDT) this is unknown. MIF mediates its effects through CD74 and/or C-X-C c...
Autores principales: | Song, Shanshan, Liu, Bin, Habibie, Habibie, van den Bor, Jelle, Smit, Martine J., Gosens, Reinoud, Wu, Xinhui, Brandsma, Corry-Anke, Cool, Robbert H., Haisma, Hidde J., Poelarends, Gerrit J., Melgert, Barbro N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185224/ https://www.ncbi.nlm.nih.gov/pubmed/34098338 http://dx.doi.org/10.1016/j.ebiom.2021.103412 |
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