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A refined genome phage display methodology delineates the human antibody response in patients with Chagas disease

Large-scale mapping of antigens and epitopes is pivotal for developing immunotherapies but challenging, especially for eukaryotic pathogens, owing to their large genomes. Here, we developed an integrated platform for genome phage display (gPhage) to show that unbiased libraries of the eukaryotic par...

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Detalles Bibliográficos
Autores principales: Teixeira, André Azevedo Reis, Carnero, Luis Rodriguez, Kuramoto, Andréia, Tang, Fenny Hui Fen, Gomes, Carlos Hernique, Pereira, Natalia Bueno, de Oliveira, Léa Campos, Garrini, Regina, Monteiro, Jhonatas Sirino, Setubal, João Carlos, Sabino, Ester Cerdeira, Pasqualini, Renata, Colli, Walter, Arap, Wadih, Alves, Maria Júlia Manso, Cunha-Neto, Edécio, Giordano, Ricardo José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185243/
https://www.ncbi.nlm.nih.gov/pubmed/34142048
http://dx.doi.org/10.1016/j.isci.2021.102540