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A refined genome phage display methodology delineates the human antibody response in patients with Chagas disease
Large-scale mapping of antigens and epitopes is pivotal for developing immunotherapies but challenging, especially for eukaryotic pathogens, owing to their large genomes. Here, we developed an integrated platform for genome phage display (gPhage) to show that unbiased libraries of the eukaryotic par...
Autores principales: | Teixeira, André Azevedo Reis, Carnero, Luis Rodriguez, Kuramoto, Andréia, Tang, Fenny Hui Fen, Gomes, Carlos Hernique, Pereira, Natalia Bueno, de Oliveira, Léa Campos, Garrini, Regina, Monteiro, Jhonatas Sirino, Setubal, João Carlos, Sabino, Ester Cerdeira, Pasqualini, Renata, Colli, Walter, Arap, Wadih, Alves, Maria Júlia Manso, Cunha-Neto, Edécio, Giordano, Ricardo José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185243/ https://www.ncbi.nlm.nih.gov/pubmed/34142048 http://dx.doi.org/10.1016/j.isci.2021.102540 |
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