Cargando…

Autonomous Robotic Point-of-Care Ultrasound Imaging for Monitoring of COVID-19–Induced Pulmonary Diseases

The COVID-19 pandemic has emerged as a serious global health crisis, with the predominant morbidity and mortality linked to pulmonary involvement. Point-of-Care ultrasound (POCUS) scanning, becoming one of the primary determinative methods for its diagnosis and staging, requires, however, close cont...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Zogbi, Lidia, Singh, Vivek, Teixeira, Brian, Ahuja, Avani, Bagherzadeh, Pooyan Sahbaee, Kapoor, Ankur, Saeidi, Hamed, Fleiter, Thorsten, Krieger, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185340/
https://www.ncbi.nlm.nih.gov/pubmed/34113656
http://dx.doi.org/10.3389/frobt.2021.645756
_version_ 1783704770550169600
author Al-Zogbi, Lidia
Singh, Vivek
Teixeira, Brian
Ahuja, Avani
Bagherzadeh, Pooyan Sahbaee
Kapoor, Ankur
Saeidi, Hamed
Fleiter, Thorsten
Krieger, Axel
author_facet Al-Zogbi, Lidia
Singh, Vivek
Teixeira, Brian
Ahuja, Avani
Bagherzadeh, Pooyan Sahbaee
Kapoor, Ankur
Saeidi, Hamed
Fleiter, Thorsten
Krieger, Axel
author_sort Al-Zogbi, Lidia
collection PubMed
description The COVID-19 pandemic has emerged as a serious global health crisis, with the predominant morbidity and mortality linked to pulmonary involvement. Point-of-Care ultrasound (POCUS) scanning, becoming one of the primary determinative methods for its diagnosis and staging, requires, however, close contact of healthcare workers with patients, therefore increasing the risk of infection. This work thus proposes an autonomous robotic solution that enables POCUS scanning of COVID-19 patients’ lungs for diagnosis and staging. An algorithm was developed for approximating the optimal position of an ultrasound probe on a patient from prior CT scans to reach predefined lung infiltrates. In the absence of prior CT scans, a deep learning method was developed for predicting 3D landmark positions of a human ribcage given a torso surface model. The landmarks, combined with the surface model, are subsequently used for estimating optimal ultrasound probe position on the patient for imaging infiltrates. These algorithms, combined with a force–displacement profile collection methodology, enabled the system to successfully image all points of interest in a simulated experimental setup with an average accuracy of 20.6 ± 14.7 mm using prior CT scans, and 19.8 ± 16.9 mm using only ribcage landmark estimation. A study on a full torso ultrasound phantom showed that autonomously acquired ultrasound images were 100% interpretable when using force feedback with prior CT and 88% with landmark estimation, compared to 75 and 58% without force feedback, respectively. This demonstrates the preliminary feasibility of the system, and its potential for offering a solution to help mitigate the spread of COVID-19 in vulnerable environments.
format Online
Article
Text
id pubmed-8185340
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-81853402021-06-09 Autonomous Robotic Point-of-Care Ultrasound Imaging for Monitoring of COVID-19–Induced Pulmonary Diseases Al-Zogbi, Lidia Singh, Vivek Teixeira, Brian Ahuja, Avani Bagherzadeh, Pooyan Sahbaee Kapoor, Ankur Saeidi, Hamed Fleiter, Thorsten Krieger, Axel Front Robot AI Robotics and AI The COVID-19 pandemic has emerged as a serious global health crisis, with the predominant morbidity and mortality linked to pulmonary involvement. Point-of-Care ultrasound (POCUS) scanning, becoming one of the primary determinative methods for its diagnosis and staging, requires, however, close contact of healthcare workers with patients, therefore increasing the risk of infection. This work thus proposes an autonomous robotic solution that enables POCUS scanning of COVID-19 patients’ lungs for diagnosis and staging. An algorithm was developed for approximating the optimal position of an ultrasound probe on a patient from prior CT scans to reach predefined lung infiltrates. In the absence of prior CT scans, a deep learning method was developed for predicting 3D landmark positions of a human ribcage given a torso surface model. The landmarks, combined with the surface model, are subsequently used for estimating optimal ultrasound probe position on the patient for imaging infiltrates. These algorithms, combined with a force–displacement profile collection methodology, enabled the system to successfully image all points of interest in a simulated experimental setup with an average accuracy of 20.6 ± 14.7 mm using prior CT scans, and 19.8 ± 16.9 mm using only ribcage landmark estimation. A study on a full torso ultrasound phantom showed that autonomously acquired ultrasound images were 100% interpretable when using force feedback with prior CT and 88% with landmark estimation, compared to 75 and 58% without force feedback, respectively. This demonstrates the preliminary feasibility of the system, and its potential for offering a solution to help mitigate the spread of COVID-19 in vulnerable environments. Frontiers Media S.A. 2021-05-25 /pmc/articles/PMC8185340/ /pubmed/34113656 http://dx.doi.org/10.3389/frobt.2021.645756 Text en Copyright © 2021 Al-Zogbi, Singh, Teixeira, Ahuja, Bagherzadeh, Kapoor, Saeidi, Fleiter and Krieger. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Robotics and AI
Al-Zogbi, Lidia
Singh, Vivek
Teixeira, Brian
Ahuja, Avani
Bagherzadeh, Pooyan Sahbaee
Kapoor, Ankur
Saeidi, Hamed
Fleiter, Thorsten
Krieger, Axel
Autonomous Robotic Point-of-Care Ultrasound Imaging for Monitoring of COVID-19–Induced Pulmonary Diseases
title Autonomous Robotic Point-of-Care Ultrasound Imaging for Monitoring of COVID-19–Induced Pulmonary Diseases
title_full Autonomous Robotic Point-of-Care Ultrasound Imaging for Monitoring of COVID-19–Induced Pulmonary Diseases
title_fullStr Autonomous Robotic Point-of-Care Ultrasound Imaging for Monitoring of COVID-19–Induced Pulmonary Diseases
title_full_unstemmed Autonomous Robotic Point-of-Care Ultrasound Imaging for Monitoring of COVID-19–Induced Pulmonary Diseases
title_short Autonomous Robotic Point-of-Care Ultrasound Imaging for Monitoring of COVID-19–Induced Pulmonary Diseases
title_sort autonomous robotic point-of-care ultrasound imaging for monitoring of covid-19–induced pulmonary diseases
topic Robotics and AI
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185340/
https://www.ncbi.nlm.nih.gov/pubmed/34113656
http://dx.doi.org/10.3389/frobt.2021.645756
work_keys_str_mv AT alzogbilidia autonomousroboticpointofcareultrasoundimagingformonitoringofcovid19inducedpulmonarydiseases
AT singhvivek autonomousroboticpointofcareultrasoundimagingformonitoringofcovid19inducedpulmonarydiseases
AT teixeirabrian autonomousroboticpointofcareultrasoundimagingformonitoringofcovid19inducedpulmonarydiseases
AT ahujaavani autonomousroboticpointofcareultrasoundimagingformonitoringofcovid19inducedpulmonarydiseases
AT bagherzadehpooyansahbaee autonomousroboticpointofcareultrasoundimagingformonitoringofcovid19inducedpulmonarydiseases
AT kapoorankur autonomousroboticpointofcareultrasoundimagingformonitoringofcovid19inducedpulmonarydiseases
AT saeidihamed autonomousroboticpointofcareultrasoundimagingformonitoringofcovid19inducedpulmonarydiseases
AT fleiterthorsten autonomousroboticpointofcareultrasoundimagingformonitoringofcovid19inducedpulmonarydiseases
AT kriegeraxel autonomousroboticpointofcareultrasoundimagingformonitoringofcovid19inducedpulmonarydiseases