Cargando…

Expression of the SARS-CoV-2 Receptor ACE2 in Human Retina and Diabetes—Implications for Retinopathy

PURPOSE: To investigate the expression of angiotensin-converting enzyme 2 (ACE2), the receptor for SARS-CoV-2 in human retina. METHODS: Human post-mortem eyes from 13 non-diabetic control cases and 11 diabetic retinopathy cases were analyzed for the expression of ACE2. To compare the vascular ACE2 e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Lingli, Xu, Zhenhua, Guerra, James, Rosenberg, Avi Z., Fenaroli, Paride, Eberhart, Charles G., Duh, Elia J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2021
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185397/ https://www.ncbi.nlm.nih.gov/pubmed/34086044 http://dx.doi.org/10.1167/iovs.62.7.6

Ejemplares similares

Metabolomics Analyses of Mouse Retinas in Oxygen-Induced Retinopathy
por: Zhou, Yedi, et al.
Publicado: (2021)

Monomethyl Fumarate Protects the Retina From Light-Induced Retinopathy
por: Jiang, Dan, et al.
Publicado: (2019)

Evidence for Structural and Functional Damage of the Inner Retina in Diabetes With No Diabetic Retinopathy
por: Montesano, Giovanni, et al.
Publicado: (2021)

CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression
por: Vos, Sarah, et al.
Publicado: (2023)

ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection
por: Zhou, Lingli, et al.
Publicado: (2020)

Sox2-Deficient Müller Glia Disrupt the Structural and Functional Maturation of the Mammalian Retina
por: Bachleda, Amelia R., et al.
Publicado: (2016)

The Effects of Metformin on Obesity-Induced Dysfunctional Retinas
por: Kim, Andy Jeesu, et al.
Publicado: (2017)

The Retina in Alzheimer's Disease: Histomorphometric Analysis of an Ophthalmologic Biomarker
por: Asanad, Samuel, et al.
Publicado: (2019)

Diabetes Reshapes the Circadian Transcriptome Profile in Murine Retina
por: Ye, Suna, et al.
Publicado: (2023)

Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina
por: Carroll, Lara S., et al.
Publicado: (2019)

Blockade of Annexin A2 Prevents Early Microvasculopathy in Murine Models of Diabetic Retinopathy
por: Dallacasagrande, Valentina, et al.
Publicado: (2023)

Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy
por: Liu, Haitao, et al.
Publicado: (2019)

Conditional Deletion of AP-2α and AP-2β in the Developing Murine Retina Leads to Altered Amacrine Cell Mosaics and Disrupted Visual Function
por: Hicks, Emily Anne, et al.
Publicado: (2018)

Epithelial Membrane Protein 2 (EMP2) Promotes VEGF-Induced Pathological Neovascularization in Murine Oxygen-Induced Retinopathy
por: Sun, Michel, et al.
Publicado: (2020)

Intravitreal Administration of AAV2-SIRT1 Reverses Diabetic Retinopathy in a Mouse Model of Type 2 Diabetes
por: Adu-Agyeiwaah, Yvonne, et al.
Publicado: (2023)

Mutation in the Zebrafish cct2 Gene Leads to Abnormalities of Cell Cycle and Cell Death in the Retina: A Model of CCT2-Related Leber Congenital Amaurosis
por: Minegishi, Yuriko, et al.
Publicado: (2018)

CD40 Expressed in Endothelial Cells Promotes Upregulation of ICAM-1 But Not Pro-Inflammatory Cytokines, NOS2 and P2X(7) in the Diabetic Retina
por: Yu, Jin-Sang, et al.
Publicado: (2021)

Elongation of the Retina and Ciliary Body in Dependence of the Sagittal Eye Diameter
por: Panda-Jonas, Songhomitra, et al.
Publicado: (2022)

Sortilin Inhibition Protects Neurons From Degeneration in the Diabetic Retina
por: Jakobsen, Thomas Stax, et al.
Publicado: (2023)

Improvement of Photoreceptor Targeting via Intravitreal Delivery in Mouse and Human Retina Using Combinatory rAAV2 Capsid Mutant Vectors
por: Reid, Christopher A., et al.
Publicado: (2017)

Survey of the use of laser protective eyewear among international retina specialists: a European vitreoretinal society study
por: Siddiqui, Mohammad Z, et al.
Publicado: (2021)

Monocarboxylate Transporter 1 (MCT1) Mediates Succinate Export in the Retina
por: Bisbach, Celia M., et al.
Publicado: (2022)

Quantitative Fundus Autofluorescence in HCQ Retinopathy
por: Greenstein, Vivienne C., et al.
Publicado: (2020)

Correlation of Optical Coherence Tomography and Autofluorescence in the Outer Retina and Choroid of Patients With Choroideremia
por: Xue, Kanmin, et al.
Publicado: (2016)

Imaging of Macrophage-Like Cells in Living Human Retina Using Clinical OCT
por: Castanos, Maria V., et al.
Publicado: (2020)

A Novel Device for Suprachoroidal Drug Delivery to Retina: Evaluation in Nonhuman Primates
por: Rotenstreich, Ygal, et al.
Publicado: (2023)

Arginine and Carnitine Metabolites Are Altered in Diabetic Retinopathy
por: Sumarriva, Katherine, et al.
Publicado: (2019)

Targeted Blood Metabolomic Study on Retinopathy of Prematurity
por: Yang, Yuhang, et al.
Publicado: (2020)

The Impact of Diabetic Retinopathy on the Choriocapillaris in Neovascular AMD
por: Viggiano, Pasquale, et al.
Publicado: (2023)

Clinical Characteristics of Neuronal Intranuclear Inclusion Disease-Related Retinopathy With CGG Repeat Expansions in the NOTCH2NLC Gene
por: Nakamura, Natsuko, et al.
Publicado: (2020)

Peripapillary Retinal Nerve Fiber Layer and Microvasculature in Prolonged Type 2 Diabetes Patients Without Clinical Diabetic Retinopathy
por: Lee, Min-Woo, et al.
Publicado: (2021)

Prenatal Carotenoid Supplementation With Lutein or Zeaxanthin Ameliorates Oxygen-Induced Retinopathy (OIR) in Bco2(−/−) Macular Pigment Mice
por: Arunkumar, Ranganathan, et al.
Publicado: (2023)

Lycium Barbarum Polysaccharides Protect Retina in rd1 Mice During Photoreceptor Degeneration
por: Liu, Feng, et al.
Publicado: (2018)

Evaluating Signs of Microangiopathy Secondary to Diabetes in Different Areas of the Retina with Swept Source OCTA
por: Karst, Sonja G., et al.
Publicado: (2020)

Beneficial and Detrimental Pressure-Related Effects on Inner Neurons in the Adult Porcine In Vitro Retina
por: Svare, Frida, et al.
Publicado: (2023)

Pro-inflammatory cytokine profile is present in the serum of Mexican patients with different stages of diabetic retinopathy secondary to type 2 diabetes
por: Quevedo-Martínez, Jonathan Uriel, et al.
Publicado: (2021)

Complement Activation in the Vitreous of Patients With Proliferative Diabetic Retinopathy
por: Mandava, Nikhil, et al.
Publicado: (2020)

Plasma and Vitreous Metabolomics Profiling of Proliferative Diabetic Retinopathy
por: Wang, Hanying, et al.
Publicado: (2022)

Assessment of the Retina of Plp-α-Syn Mice as a Model for Studying Synuclein-Dependent Diseases
por: Kaehler, Kathrin, et al.
Publicado: (2020)

Functional Correlates of Outer Retina Remodeling in Intermediate Age-Related Macular Degeneration Using Microperimetry
por: Fragiotta, Serena, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_e7fqnarfp2u7h12sg8gful7un5