ARCAM-1 Facilitates Fluorescence Detection of Amyloid-Containing Deposits in the Retina

PURPOSE: To investigate the use of an amyloid-targeting fluorescent probe, ARCAM-1, to identify amyloid-containing deposits in the retina of a transgenic mouse model of Alzheimer's disease (AD) and in human postmortem AD patients. METHODS: Aged APP/PS1 transgenic AD and wild-type (WT) mice were...

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Detalles Bibliográficos
Autores principales: Cao, Kevin J., Kim, John H., Kroeger, Heike, Gaffney, Patricia M., Lin, Jonathan H., Sigurdson, Christina J., Yang, Jerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185402/
https://www.ncbi.nlm.nih.gov/pubmed/34096989
http://dx.doi.org/10.1167/tvst.10.7.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185402/
https://www.ncbi.nlm.nih.gov/pubmed/34096989
http://dx.doi.org/10.1167/tvst.10.7.5

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